Circulating ghrelin levels are decreased in human obesity.

By Matthias Tschöp, C. Weyer, P. Tataranni, V. Devanarayan, E. Ravussin, M. Heiman. Diabetes, 2001

2,091 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Nutrition and Dietetics, Physiology

View Paper: https://www.semanticscholar.org/paper/dc2c29180f6c6e6a4341f7d0d087e236a159477d

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In Endocrine and Autonomic Systems

In Nutrition and Dietetics

In Physiology

Citations in the corpus

Weight Loss, Appetite Suppression, and Changes in Fasting and Postprandial Ghrelin and Peptide-YY Levels After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy: A Prospective, Double Blind Study (2008, background): “Circulating ghrelin levels are decreased in human obesity.(12) In an initial study, ghrelin levels increased after diet induced weight loss, whereas weight loss after gastric bypass was associated with markedly suppressed ghrelin levels.”
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. (2001, background): “Human plasma ghrelin levels were reported in one recent study (13), but only fasting values were examined.”
The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review (2007, background): “demonstrated that in obese patients fasting plasma ghrelin levels are negatively correlated with fasting plasma leptin levels (60).”
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. (2004, background): “Several recent studies show that circulating ghrelin peptide levels are decreased in obese individuals (202, 219, 444, 445) as well as postprandially (242), whereas ghrelin levels are increased under cachectic and anorectic conditions (245, 416, 446, 447), as well as during food deprivation (33, 243”
Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. (2002, background): “(19) have measured plasma ghrelin concentrations in normal and obese Caucasian and Pima Indian individuals.”
Ghrelin: structure and function. (2005, background): “Plasma ghrelin concentration is low in obese people and high in lean people (23, 51, 98, 99, 200, 209, 248).”
Ghrelin controls hippocampal spine synapse density and memory performance (2006, background): “Because both aging and obesity are associated with low ghrelin level”
Ghrelin enhances appetite and increases food intake in humans. (2001, background): “A recent report has demonstrated reduced circulating ghrelin in obese compared with lean Caucasians and in obesity-prone Pima Indians (20).”