Evolutionary Aspects of Diet: The Omega-6/Omega-3 Ratio and the Brain

By A. Simopoulos. Molecular Neurobiology, 2011

610 citations recorded by the source corpus.

Subfields: Nutrition and Dietetics, Physiology, Surgery

View Paper: https://www.semanticscholar.org/paper/dbac7208054dab9c11ee651d32feb7ed156ce37c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Nutrition and Dietetics

1. Bhanu Sharma
2. M. T. Arts
3. R. Ross
4. C. Parrish
5. G. FitzGerald
6. Rebecca Wall
7. C. Stanton
8. E. Patterson

In Physiology

1. Rosa Krajmalnik-Brown
2. M. T. Arts
3. R. Ross
4. C. Parrish
5. G. FitzGerald
6. Rebecca Wall
7. Dae-Wook Kang
8. C. Stanton

In Surgery

1. Bhanu Sharma
2. M. T. Arts
3. C. Stanton
4. Alexander Wacker
5. M. Kainz
6. S. Hixson

Citations in the corpus

• Health Implications of High Dietary Omega-6 Polyunsaturated Fatty Acids (2012, background): “Today, industrialised societies are characterised by an increase in saturated fat, omega 6 PUFA, and trans fatty acid intake, as well as an overall decrease in omega-3 PUFA intake [5].”
• Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children (2013, background): “Fish oil is a precursor of omega-3 fatty acids, which are beneficial for normal brain development [54].”
• Production, distribution, and abundance of long-chain omega-3 polyunsaturated fatty acids: a fundamental dichotomy between freshwater and terrestrial ecosystems (2015, background): “, ≥20 carbons long) polyunsaturated fatty acids (LC-PUFA) are critically involved with key physiological functions of aquatic and terrestrial vertebrates, including humans, in supporting brain function, cardiovascular health, growth, reproduction, and the immune response (Arts et al. 2001; Brenna et”
• A fundamental dichotomy in long-chain polyunsaturated fatty acid abundance between and within marine and terrestrial ecosystems (2017, background): “…to have key physiological functions in all vertebrate organisms, specifically involved in supporting neurological development and function, cardiovascular health, visual acuity, growth, reproduction, and the immune system (Brenna et al. 2009; Simopoulos 2011; Swanson et al. 2012; Calder 2015).”
• The bioavailability of an omega-3-rich algal oil is improved by nanoemulsion technology using yogurt as a food vehicle (2014, background): “269 270 Changes in ARA:EPA ratios 271 The ratio of omega-6 (n-6) to n-3 is important for long-term health and the arachidonic 272 acid/eicosapentaenoic acid (ARA/EPA) ratio may be used as an indicator of fatty acid balance and 273 long-term health (Simopoulos 2011).”
• A comparative study on the effect of fish meal substitution with three different insect meals on growth, body composition and metabolism of European sea bass (Dicentrarchus labrax L.) (2020, neutral): “…f addition, all experimental diets resulted in a whole-body n-6/n-3 ratio (0.27-0.72) below the suggested limit for healthy human nutrition (1-2:1) (Simopoulos, 2011). r Such great differences in the fatty acid composition might affect organoleptic characteristics of the fish flesh, e.g. p aroma…”
• Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis (2020, background): “Thus, it is recommended to keep a healthy balance between omega-6 and omega-3, with a ratio of 1:1–4:1 [139,140].”