MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias.

By George A. Calin, Chang-Gong Liu, C. Sevignani, M. Ferracin, N. Felli, C. Dumitru, M. Shimizu, A. Cimmino, S. Zupo, M. Dono and 7 more. Proceedings of the National Academy of Sciences of the United States of America, 2004

1,351 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d577f656be9a1aa6d951dfd8cb02867d7194f4a8

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Citations in the corpus

A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes (2006, background): “These miRNAs are known to be contained within a genomic interval frequently deleted in myelodysplastic syndrome (Calin et al., 2004b).”
MicroRNA-cancer connection: the beginning of a new tale. (2006, background): “Cancer-specific miRNA fingerprints were identified in every type of analyzed cancer, including B-CLL (10), breast carcinoma (11), primary glioblastoma (12), hepatocellular carcinoma (13), papillary thyroid carcinoma (14), lung cancer (15–17), gastric carcinoma, colon carcinoma (18), and endocrine pa”
microRNA as Biomarkers and Diagnostics (2016, background): “…fully explored. miRNAs as Biomarkers for Cancers Many human miRNAs appear to be located in genomic regions associated with cancer or at fragile sites (Calin et al., 2004b) and control important processes such as cell proliferation, cell adhesion, apoptosis, and angiogenesis, dysregulation of which…”
MicroRNA gene expression deregulation in human breast cancer. (2005, background): “The same two genes were affected by a chromosomal translocation in a CLL patient. mir-16-1 and/or mir-15a were then found down-regulated in 50% to 60% of human CLL (4).”
MicroRNA functions in animal development and human disease (2005, background): “Many microRNAs are de-regulated in primary human tumours (Calin et al., 2002; Calin et al., 2004a; He et al., 2005; Lu et al., 2005).”
MiR-15a and miR-16-1 cluster functions in human leukemia (2008, result): “Therefore, to verify whether some of the targets of miR-15a/16-1 identified in MEG-01 cells were inversely correlated to the expression of these two miRNAs in CLL patients, we selected a group of 16 CLL samples in whom the expression of miR-15a/16-1 had already been determined by miRNA microarray an”
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. (2006, background): “…carcinoma; mlncRNA, mRNA-like noncoding RNA; ND, not defined; MFHs, malignant fibrous histocytomas. aInformation was obtained from previous report (Calin et al., 2004b). bInformation was obtained from previous report (Rodriguez et al., 2004). proportional hazard regression analysis using all of…”