Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA
By M. Falkenberg, M. Gaspari, A. Rantanen, A. Trifunovic, N. Larsson, C. Gustafsson. Nature Genetics, 2002
625 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/d06599a7abf67711a47b81b96a05d105d133e66e
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Citations in the corpus
- The mitochondrial p53 pathway (2008, positive): “Major mitochondrial transcription factors are mtTFA and TFBM1 and 2, which regulate the HSP and LSP promoters [55].”
- Control of Mitochondrial Transcription Specificity Factors (TFB1M and TFB2M) by Nuclear Respiratory Factors (NRF-1 and NRF-2) and PGC-1 Family Coactivators (2005, background): “Most recently, two isoforms of a human mitochondrial transcription specificity factor, termed TFB1M and TFB2M (also known as h-mtTFB), have also been identified (9, 20).”
- Transcription and transcriptional regulation in plastids (2007, background): “Despite poor overall sequence similarity, it recently has been shown that mtTFB factors belong to a family of RNA-methyltransferases (Falkenberg et al. 2002; McCulloch et al. 2002; Rantanen et al. 2003; Seidel-Rogol et al. 2003).”
- Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. (2004, background): “These include genes for Tfam (Larsson et al. 1998; Rantanen et al. 2001) and the newly discovered TFB factors (Falkenberg et al. 2002; McCulloch et al. 2002) involved in mitochondrial transcription and DNA replication (Rantanen et al. 2001).”
- Transcriptional paradigms in mammalian mitochondrial biogenesis and function. (2008, background): “Two isoforms of h-mtTFB, termed TFB1M and TFB2M, have been identified independently (65).”
- Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha. (2008, background): “Additionally, two proteins that interact with the mammalian mitochondrial RNA polymerase and Tfam, TFB1M and TFB2M, can support promoter-specific mtDNA transcription.(15) Although usually complex and promoter-specific, certain DNA binding motifs are present in the promoters of several of genes encod”