Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha.

By R. Ventura-clapier, A. Garnier, V. Veksler. Cardiovascular Research, 2008

905 citations recorded by the source corpus.

Subfields: Electrical and Electronic Engineering, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/0a4e23c3df374db00315d39de8c7fac97b0983f5

How researchers see this paper

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In Molecular Biology

1. Gerald I. Shulman
2. F. Jornayvaz
3. Ralph DeFronzo

In Physiology

1. Gerald I. Shulman
2. F. Jornayvaz
3. V. Samuel
4. Ralph DeFronzo
5. K. Petersen
6. D. Clegg
7. B. Palmer

Citations in the corpus

• PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism (2020, background): “However, in endothelial cells, NO is necessary to migration cells [111].”
• Regulation of mitochondrial biogenesis (2010, background): “In addition to NRFs, PGC-1α also interacts with and co-activates other transcription factors such as PPARs, thyroid hormone, glucocorticoid, oestrogen and ERRs (oestrogen-related receptors) α and γ [13].”
• PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson’s Disease (2011, neutral): “Since PGC-1a and NRF-1 are major transcriptional regulators of mitochondrial biogenesis (Finck and Kelly, 2006; St-Pierre et al., 2006; Ventura-Clapier et al., 2008; Wu et al., 1999), it is conceivable that when parkin decreases the number of mitochondria through mitophagy in response to mitochondri”