RNAi-mediated pathways in the nucleus

By M. Matzke, James A. Birchler. Nature reviews genetics, 2005

910 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/cc5c36079e834b1399ee11ed3cc0907654d159c2

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Citations in the corpus

Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution (2009, neutral): “Four types of cellular EISs are recognized today: the EIS based on self-sustaining regulatory loops, the EIS based on three-dimensional Fi g u re 1.”
Antiviral immunity directed by small RNAs. (2007, neutral): “No antiviral role has been ascribed so far to RDR2, involved in the DCL3-AGO4 heterochromatic silencing pathway (Matzke and Birchler, 2005).”
DNA methylation: The nuts and bolts of repression (2007, background): “In plants RNAi-mediated silencing can result in de novo methylation of genes (Matzke and Birchler, 2005).”
Strategies for silencing human disease using RNA interference (2007, background): “RNAi pathways can also direct transcriptional gene silencing (TGS) in the nucleu”
Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs. (2005, background): “Endogenous 21–24 nt small RNAs regulate gene expression transcriptionally or posttranscriptionally [6–8].”
Nutrition and epigenetics: An interplay of dietary methyl donors, one-carbon metabolism, and DNA methylation (2012, neutral): “Epigenetic modifications include chromatin remodeling, histone tail modifications, DNA methylation and, more recently, have expanded to include non-coding RNA and microRNA gene regulation [3].”
Soft inheritance: challenging the modern synthesis (2008, background): “Transcriptional states are actively maintained through interactions between small, transmissible, RNA molecules and the mRNAs or the DNA/chromatin regions with which they pair (Bernstein and Allis, 2005; Matzke and Birchler, 2005).”
MicroRNA-directed transcriptional gene silencing in mammalian cells (2008, background): “S noncoding RNAs regulate epigenetic gene silencing pathways that are well-conserved in eukaryotes (1, 2).”
TRBP, a regulator of cellular PKR and HIV‐1 virus expression, interacts with Dicer and functions in RNA silencing (2005, background): “Moreover, it has become increasingly apparent that both pathways intersect with several other cellular processes, such as chromosome segregation (Matzke & Birchler, 2005), RNA editing (Scadden, 2005) and nonsense-mediated degradation (Domeier et al, 2000; Kim et al, 2005).”
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. (2007, background): “In Arabidopsis, it is well established that the RNAi machinery can use small RNAs to direct genomic methylation, though the precise biochemical mechanism underlying these events remains unclear (Matzke and Birchler, 2005).”
Genetic containment of forest plantations (2007, background): “Double-stranded RNA (dsRNA) can induce a variety of sequence-specific gene suppression processes in plants, animals, and fungi (reviewed in Baulcombe 2004; Matzke and Birchler 2005).”
Active DNA Demethylation Mediated by DNA Glycosylases (2009, neutral): “In plants, siRNAs of the 24-nt size class can trigger cytosine methylation and consequent transcriptional silencing of homologous DNA (4, 63, 64).”