MicroRNAs: new regulators of immune cell development and function

By David Baltimore, M. Boldin, Ryan M. O’Connell, D. Rao, K. Taganov. Nature Immunology, 2008

1,142 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cbf1b454e50928fe9e65ec48609fd4ee73c0cd5a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

In Molecular Biology

Citations in the corpus

Transcriptional control of the inflammatory response (2009, background): “The role of microRNAs in this process has been recently reviewe”
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ (2011, background): “2073" language="eng" relation="no"> MicroRNAs (miRNAs) have been identified as important regulators of many biological systems, including mammalian immune system”
Epigenetic control of T-helper-cell differentiation (2009, background): “Epigenetic processes that influence mRNA splicing, stability and translation in the immune system, such as microRNAs, have been reviewed recentl”
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells (2009, background): “miR-155 is contained within the noncoding B cell integration cluster (Bic) gene (13) and has been linked to B and T cell immunity (9, 14, 15).”
Differentiation of Effector CD4 T Cell Populations (2010, positive): “Not surprisingly, many reports indicate that miRNAs play important roles in regulating virtually all biological processes including hematopoiesis and the functions of immune cells, including T cells (269).”
Physiological and pathological roles for microRNAs in the immune system (2010, background): “jpg"/> The recent discovery of microRNAs (miRNAs) has revealed a new layer of gene expression regulation that affects many biological systems, including the mammalian immune syste”
Akt1 controls macrophage response to LPS by regulating microRNAs (2009, background): “Recent studies have identified miRNAs as critical regulators of immune responses including inflammation (Baltimore et al., 2008; Chong et al., 2008; Cobb et al., 2006; Liston et al., 2008; Lu et al., 2009; Xiao and Rajewsky, 2009; Zhou et al., 2008).”
miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice (2011, background): “A growing body of evidence suggests that the development and function of cells in the immune system is particularly subject to regulation by miRNAs (Baltimore et al., 2008; Tsitsiou and Lindsay, 2009).”