Epigenetic control of T-helper-cell differentiation

By Christopher B Wilson, Emily Rowell, M. Sekimata. Nature reviews. Immunology, 2009

721 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/923e65b5269f5148fe34bf73a603447103fb1958

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In Immunology

1. Jinfang Zhu
2. W. E. Paul
3. Dan R. Littman
4. D. Campbell
5. M. Chong
6. H. Yamane
7. M. Koch
8. Liang Zhou

In Molecular Biology

1. W. E. Paul
2. Dan R. Littman
3. Jinfang Zhu
4. H. Yamane

Citations in the corpus

• Plasticity of CD4+ T cell lineage differentiation. (2009, background): “…View of T Helper Cell Differentiation The differentiation of T helper cells is intricately coupled to epigenetic changes in chromatin structure, histone and DNA modifications, and the expression of small noncoding RNAs (Ansel et al., 2003; Merkenschlager and Wilson, 2008; Wilson et al., 2009).”
• Differentiation of Effector CD4 T Cell Populations (2010, positive): “Many transcription factors, including T-bet, STAT4, Runx3, STAT5, and CTCF, bind to different regions of the Ifng gene (65, 131, 144, 181, 243, 261, 262).”
• T-bet controls regulatory T cell homeostasis and function during type-1 inflammation (2009, background): “This functional specialization is due to differences in the expression of transcription factors that initiate distinct programs of gene expression controlling cytokine production and migratio”