Purification of a pluripotent neural stem cell from the adult mouse brain

By R. Rietze, H. Valcanis, G. J. Brooker, T. Thomas, A. Voss, P. Bartlett. Nature, 2001

680 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Genetics

View Paper: https://www.semanticscholar.org/paper/caa8cdf429ec8549112efb86bd337b8e9a3e6dfe

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Fred H. Gage
2. Hongjun Song
3. Guo-li Ming
4. D. C. Lie
5. F. Doetsch
6. J. Ray
7. M. Götz
8. P. Taupin

In Developmental Neuroscience

1. Fred H. Gage
2. Hongjun Song
3. Guo-li Ming
4. F. Doetsch
5. Arturo Alvarez-Buylla
6. D. C. Lie
7. M. Götz
8. J. Ray

In Genetics

1. Hongjun Song
2. Guo-li Ming
3. Fred H. Gage
4. P. Zammit
5. T. Partridge
6. J. Ray
7. D. C. Lie
8. Sally Temple

Citations in the corpus

• Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. (2006, background): “The expression of smooth muscle, endothelial cell, and cartilage markers by Mes tumors is reminiscent of the reported multipotentiality of neural stem cells from adult forebrain (Bani-Yaghoub et al., 2004; Rietze et al., 2001; Sieber-Blum, 2003; Wurmser et al., 2004).”
• Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation (2003, background): “p16 Ink4a was also upregulated in uncultured Bmi-1 -/- P30 SVZ FSC hi SSEA-1 hi CD24 -/lo cells, which are enriched for CNS stem cell”
• In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. (2010, background): “, 2009) or the isolated fraction contained only a proportion of the stem cells (Rietze et al., 2001).”
• GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain (2004, neutral): “In contrast, using flow cytometry, one study found no immunohistochemical evidence for GFAP expressio”
• The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold (2006, methodology): “…presumably because the conditions used for their fluorescence-activated cell sorting (FACS) isolation (e.g., enzymatic digestion conditions used prior to FACS and/or concentration of Hoechst dye) dictate the range of cells included in the SP fraction (Montanaro et al. 2004; Rivier et al. 2004).”
• The glial identity of neural stem cells (2003, background): “A nestin + /GFAP − cell, negative for both heat-stable antigen and peanut agglutini”
• Brain tumour stem cells (2006, neutral): “The situation is now improving with the identification of cell-surface antigens and methods that are used to identify putative neural stem cells in rodent”
• Adult neurogenesis and neural stem cells of the central nervous system in mammals (2002, methodology): “, 2000b), and from the lateral ventricle wall of adult mice by negative selection (Rietze et al., 2001).”
• In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. (2007, background): “…cell-surface markers or GFP expression driven by NSCspecific promoters were plated in the presence of growth factors and examined to determine whether they could expand to form neurospheres or monolayered colonies (Kawaguchi et al., 2001; Ray and Gage, 2006; Rietze et al., 2001; Roy et al., 2000).”