Human cortical glial tumors contain neural stem‐like cells expressing astroglial and neuronal markers in vitro

By T. Ignatova, V. G. Kukekov, E. Laywell, O. Suslov, F. Vrionis, D. Steindler. Glia, 2002

1,040 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ca09284d7ddbbcf67f69467d0b7ef6516f8fa54b

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Citations in the corpus

Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay For Stem Cells (2011, background): “Later experiments in which dividing GFAP+ cells were killed in GFAP-TK mice confirmed that GFAP+ cells are the source of adult generated neurons (Garcı́a et al., 2004; Imura et al., 2003; Morshead et al., 2003).”
Radial glia cells are candidate stem cells of ependymoma. (2005, background): “Neurosphere (hereon termed tumor sphere)-forming cells isolated from medulloblastoma and glioma express the neural stem cell marker CD133 and exhibit the ability to self-renew and differentiate along divergent neuronal lines (Hemmati et al., 2003; Ignatova et al., 2002; Singh et al., 2003; Uchida et”
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. (2006, background): “, 2004) and that human GBMs contain tumorigenic neural stemlike cells (Galli et al., 2004; Ignatova et al., 2002; Singh et al., 2004) indicate that neural stem and/or progenitor cells are a plausible origin for human gliomas and have given rise to speculation that more effective therapies will resul”
Identification of human brain tumour initiating cells (2004, background): “Several studies have identified stem-like cells in brain tumour culture”
Cancer stem cells in nervous system tumors (2004, background): “…of sphere formation in cultured brain tumor cells exist (Mackillop et al., 1985) and stem-like cells have been observed in brain tumor cultures (Ignatova et al., 2002), a prospectively isolated population of cancer stem cells from brain tumors had not been described until recently (Singh et…”
Isolation of cancer stem cells from adult glioblastoma multiforme (2004, background): “GBMs contain cells that express neural markers as well as cells that express glial markers, indicating that there may be multipotent neural stem cell-like cells (Ignatova et al., 2002; Katsetos et al., 2002).”
Differences between human and mouse embryonic stem cells. (2004, background): “23742 F: AGTGTGAAGGCAAAGATAGC This laboratory X65964 F: CAGCGTTGGAACAGAGGTTGG (Ignatova et al., 2002) R: TCTGTCAGGATTGGGATGGG R:TGGCACAGGTGTCTCAAGGGTAG beta 3 tubulin Mm.”
Applying the principles of stem-cell biology to cancer (2003, background): “Three groups have cultured cells with characteristics of CNS stem cells from various human brain tumour”