RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

By S. Sawa, M. Lochner, Naoko Satoh-Takayama, S. Dulauroy, M. Bérard, M. Kleinschek, D. Cua, J. D. Santo, G. Eberl. Nature Immunology, 2011

597 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

The microbiota regulates type 2 immunity through RORγt+ T cells (2015, background): “Cell preparation and cultures Small intestinal and colonic lamina propria cells were isolated as described previously (53).”
The role of microbiome in central nervous system disorders (2013, unknown): “functionally affected by microbiota at pathological conditions (Ochoa-Reparaz et al., 2009; Olszak et al., 2012; Sawa et al., 2011).”
Interleukin-22: immunobiology and pathology (2015, background): “IL-25 Negative Produced by epithelial cells, inhibits the production of IL-22 by ILCs (263)”
The Microbiome in Infectious Disease and Inflammation (2012, unknown): “This was attributed to microbiota-dependent IECderived IL-25, which suppresses IL-22 expression in LTi-like cells (200).”
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease (2016, background): “[19]Child Life and Health, University of Edinburgh, Edinburgh, Scotland, UK”