P bodies: at the crossroads of post-transcriptional pathways

By A. Eulalio, I. Behm-Ansmant, Elisa Izaurralde. Nature reviews. Molecular cell biology, 2007

1,004 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c70f6b25156b0d24fa4f6b4c45cf9821cdefd1f3

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Citations in the corpus

Translational control of long-lasting synaptic plasticity and memory. (2009, neutral): “…several disparate mechanisms has been reported: (1) inhibition of translation elongation, (2) inhibition of translation initiation, (3) ribosome drop-off, (4) cotranslational protein degradation, and (5) mRNA degradation (Eulalio et al., 2007; Filipowicz et al., 2008; Jackson and Standart, 2007).”
Mechanisms of microRNA‐mediated gene regulation (2007, background): “As discussed extensively in Refs [30] and [ 31 ], this model has the advantage of rationalizing much of the current literature regarding the mechanisms of miRNA function, including the disparate fates of specific regulated mRNAs.”
Getting to the root of miRNA-mediated gene silencing. (2008, background): “More recently, however, several reports showed that animal miRNAs do induce significant degradation of target mRNAs (Bagga et al., 2005; Wu and Belasco, 2005; Behm-Ansmant et al., 2006; Giraldez et al., 2006; Wu et al., 2006; Chendrimada et al., 2007; Eulalio et al., 2007a).”
Current prospects for RNA interference-based therapies (2011, background): “, although more recent work indicates that miRNA–mRNA complexes can be transported to cytoplasmic processing bodie”
Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs[OPEN] (2013, background): “While P-body formation results from miRNA repression, the loss of components required for visible P-body assembly in animals has no effect on miRNAmediated silencing (Chu and Rana, 2006; Eulalio et al., 2007b).”
P bodies and the control of mRNA translation and degradation. (2007, methodology): “…CPEB Cytoplasmic polyadenylation elementbinding protein; translational regulator Human (Wilczynska et al., 2005) Staufen RNA-binding protein Fly (Eulalio et al., 2007) Rbp1 RNA-binding protein, localizes P bodies during stress Yeast (Jang et al., 2006) TTP AU-rich element-binding protein…”
P-bodies and stress granules: possible roles in the control of translation and mRNA degradation. (2012, background): “These factors include the decapping enzyme complex Dcp1/Dcp2; the decapping activators Edc3 and the Lsm1-7 complex; factors that function to repress translation as well as to activate decapping including Dhh1/RCK/p54, Pat1 and Scd6/RAP55; the 50 to 30 exonuclease, Xrn1, and the Ccr4/Pop2/ Not deaden”
Regulation of mRNA translation and stability by microRNAs. (2010, background): “cytoplasmic structures thought to be involved in the storage or degradation of translationally repressed mRNAs (15, 16).”
The role of disordered protein regions in the assembly of decapping complexes and RNP granules (2013, background): “The molecular properties required for RNP granule assembly provide an explanation for why many granule components, including RNA, are required for granule integrity, and their depletion disperses the remaining components throughout the cytoplasm (Eulalio et al. 2007a; Parker and Sheth 2007).”