Regulation of mRNA translation and stability by microRNAs.
By M. Fabian, Nahum Sonenberg, W. Filipowicz. Annual Review of Biochemistry, 2010
3,175 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/7d5d10c5eb1bfb33f2a0f17c6fc5a80aaf2f1814
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cancer Research
- Howard Y. Chang
- Yvonne Tay
- John S. Mattick
- Kevin V. Morris
- P. Pandolfi
- W. Filipowicz
- M. Gorospe
- E. Gibb
In Molecular Biology
- Howard Y. Chang
- John S. Mattick
- Yvonne Tay
- P. Pandolfi
- David P. Bartel
- Kevin V. Morris
- Gregory J. Hannon
- W. Filipowicz
Citations in the corpus
- The rise of regulatory RNA (2014, background): “…not most protein-coding transcripts are targets for miRNA regulation 58,59 , that miRNAs can, in some cases, regulate large numbers of target mRNAs 60 , and reciprocally that many mRNAs contain target sites for many miRNAs 61 , although the implied regulatory logic of this complex multiplex…”
- CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs (2016, background): “Pre-microRNAs are then exported to the cytoplasm where they are further processed by DICER1 and loaded onto the RNA-inducible silencing complex (RISC) to be directed to target mRNAs.(28-31)”
- Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs[OPEN] (2013, background): “Multiple mechanisms of miRNA-mediated translational inhibition, such as inhibition of initiation, ribosome stalling, and ribosome dropoff, have been proposed in animals (reviewed in Fabian et al., 2010).”
- Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding (2013, positive): “MicroRNAs (miRNAs) play a key role in the posttranscriptional regulation of gene expression by guiding the association between the RNA-induced silencing complex (RISC) and target RNAs (reviewed in Fabian et al., 2010).”
- A ceRNA hypothesis: the Rosetta stone of a hidden RNA language? (2011, background): “RNA Transcripts Communicate through the ceRNA Language MicroRNAs are negative regulators of gene expression, decreasing the stability of target RNAs or limiting their translation (Fabian et al., 2010).”
- MicroRNA Functions in Stress Responses (2010, neutral): “Finally, miRNAs have two major modes of action: accelerating decay and/or inhibiting translation of their mRNA targets (Bushati and Cohen, 2007; Carthew and Sontheimer, 2009; Fabian et al., 2010).”
- The Emerging Field of RNA Nanotechnology (2010, neutral): “Small RNAs, such as riboswitch, with regulatory function”