Fatty Acid Regulation of Gene Transcription

By D. Jump. Critical reviews in clinical laboratory sciences, 2004

610 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/c5787fad29269310f593fc669514815cb339bc68

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

In Molecular Biology

In Surgery

Citations in the corpus

The multigene family of fatty acid-binding proteins (FABPs): Function, structure and polymorphism (2010, background): “Several mechanisms of gene transcription regulation mediated by FAs are reviewed by Duplus et al. (2000) and include induction of events leading to modification of a transcription factor, binding to and activation of a transcription factor, modifying themRNA stability, and also influencing the…”
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. (2005, background): “o-3 LCPUFAs act as ligands to PPAR genes; PPARs form a heterodimer with RXR in binding with DNA in promoter regions of genes involved in fatty acid transport, fatty acid binding, and PUFA desatuarion (Jump, 2004).”
Towards Fish Lipid Nutrigenomics: Current State and Prospects for Fin-Fish Aquaculture (2008, background): “Fatty acids and their derivatives are known to directly regulate the activities of a variety of transcription factors whose functions are in the control of genes responsible for fatty acid, cholesterol, and carbohydrate metabolism (Jump, 2004).”
High‐fat Diets: Modeling the Metabolic Disorders of Human Obesity in Rodents (2007, background): “This might be connected with an increased lipid oxidation in these animals due to the fish oil-induced activation of peroxisome proliferator-activated receptor (9,10).”
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. (2002, background): “It should also be noted that FFAs and many of their derivatives interact directly with transcription factors to regulate gene expression (333).”
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? (2003, background): “It also should be noted that FFAs and many of their metabolites interact directly with transcription factors to regulate gene expression, especially those involved in lipid and carbohydrate metabolism (66).”
Defining high-fat-diet rat models: metabolic and molecular effects of different fat types. (2006, background): “This can be explained by the hepatic PPAR activation induced by saturated and monounsaturated fatty acids, as recently reviewed by (Duplus et al. 2000).”
Skeletal anomalies in reared European fish larvae and juveniles. Part 2: main typologies, occurrences and causative factors (2013, background): “…and their metabolites have also been demonstrated to affect gene expression through several mechanisms including the control of several transcription factors, leading to changes in metabolism, growth and cell differentiation in mammals (Jump 2004) and fish (Oku & Umino 2008; Ytteborg et al. 2010).”