Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia.

By P. Tzou, S. Ohresser, D. Ferrandon, M. Capovilla, J. Reichhart, B. Lemaître, J. Hoffmann, J. Imler. Immunity, 2000

607 citations recorded by the source corpus.

Subfields: Immunology, Insect Science, Microbiology

View Paper: https://www.semanticscholar.org/paper/be38284a67260897475f1c1a5134b5b4d65b8dd2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. J. Hoffmann
2. B. Lemaître
3. Y. Moret
4. B. Beutler
5. N. Moran
6. Philipp Engel
7. J. Rolff
8. M. Siva‐Jothy

In Insect Science

1. J. Hoffmann
2. B. Lemaître
3. Philipp Engel
4. N. Moran
5. J. Rolff
6. Y. Moret
7. M. Siva‐Jothy
8. Nicolas Buchon

In Microbiology

1. J. Hoffmann
2. B. Lemaître
3. M. Siva‐Jothy
4. Y. Moret
5. J. Rolff
6. B. Beutler
7. Shizuo Akira
8. M. J. Lehane

Citations in the corpus

• The host defense of Drosophila melanogaster. (2007, background): “This response is triggered upon natural infection by Gramnegative bacteria and is mediated by the Imd pathway (82, 153).”
• Drosophila innate immunity: an evolutionary perspective (2002, background): “The epidermis—the cells of the digestive and genital tracts—of the tracheae and of the Malpighian tubules all produce antimicrobial peptides, which inhibit microbial growt”
• The evolution and genetics of innate immunity (2001, background): “Additionally, the response of antimicrobial peptide-encoding genes is tissue-specific, and in particular imd , rather than Toll , regulates Drosomycin in the respiratory trac”
• The gut microbiota of insects - diversity in structure and function. (2013, background): “Even within the midgut of D. melanogaster, regionalization of the immune response exists, with different receptors being expressed in different locations (Tzou et al., 2000; Buchon et al., 2009b; Bosco-Drayon et al., 2012; Neyen et al., 2012).”
• Anti‐microbial peptides: from invertebrates to vertebrates (2004, background): “The production of AMPs in these anuran gastric epithelia is reminiscent of the production of AMPs by insects and mammalian epithelia (63, 64).”
• The immune response of Drosophila (2003, background): “Furthermore, as in other animal phyla, epithelial immune reactions, which involve the local synthesis of antimicrobial peptides, are activated in response to infectio”
• Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees (2013, background): “melanogaster stock carrying the drosomycin-GFP reporter gene (60) and scored the fluorescence after the artificial infection.”
• Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. (2009, background): “, Diptericin and Attacin) in the gut upon oral infection by Gram-negative bacteria (Basset et al., 2000; Liehl et al., 2006; Nehme et al., 2007; Tzou et al., 2000).”
• Insect Immunity: An Evolutionary Ecology Perspective (2005, background): “, 2003) and produce a range of antimicrobial peptides in Drosophila (Tzou et al., 2000).”
• The biology of blood-sucking in insects (2005, neutral): “These are largely made by the fat body, but are also produced by epithelial surfaces such as the insect gut (Lehane et al., 1997; Tzou et al., 2000).”