The host defense of Drosophila melanogaster.

By B. Lemaître, J. Hoffmann. Annual Review of Immunology, 2007

3,328 citations recorded by the source corpus.

Subfields: Immunology, Insect Science, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/fe628c77b5dc718389bd9a140d12866bf7e8f414

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In Immunology

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Citations in the corpus

Temperature extremes and butterfly fitness: conflicting evidence from life history and immune function (2011, background): “The innate (primary) immune response in insects relies on both humoral and cellular mechanisms (Gillespie et al., 1997; Lemaitre & Hoffmann, 2007).”
Insect immunity and its signalling: an overview (2010, background): “The Imd pathway The Gram-negative bacteria activate antimicrobial peptide synthesis via the Imd pathway (Nappi et al., 2004; Lemaitre and Hoffmann, 2007; Aggarwal and Silverman, 2008).”
The Roles of Antimicrobial Peptides in Innate Host Defense (2009, background): “Subsequent examination of different cell types, including those of the myeloid lineage and epithelium have uncovered a wide variety of AMPs both from mammals as well as amphibians [12] fish [13], insects [14], birds [15], and plants [16].”
Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees (2013, methodology): “The level of NF-κB activation was determined by monitoring the expression of the drosomycin-GFP reporter gene that is under the control of the Toll pathway (32) in a transgenic strain of D.”
Ecological factors in the inundative use of fungal entomopathogens (2010, background): “During the past few years new discoveries (e.g., Lemaitre and Hoffmann 2007; Müller et al. 2008) indicate insect humoral immunity may be more important than previously thought, even with fungal entomopathogens.”
Genome Sequence of the Pea Aphid Acyrthosiphon pisum (2010, background): “The aphid immune system is expected to be critical in determining responses to microbial symbionts [62].”
Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections (2007, background): “Drosophila mount both cellular and cell-free, or humoral, immune responses to pathogen”
Effect of bioflocs on growth and immune activity of Pacific white shrimp, Litopenaeus vannamei postlarvae (2014, background): “…part of the mitogen-activatedprotein-kinase pathway: a large signal transduction network that can feed into other signalling networks, such as the immune-related JanusKinase-Signal transducer and activator of transcription (JAKSTAT) pathway, and cellular immune responses (Lemaitre & Hoffmann 2007).”
The gut microbiota of insects - diversity in structure and function. (2013, background): “Some insect species provide useful laboratory models for experimental work on microbial communities and their interactions with hosts, particularly for the understanding of immunity and metabolic interactions (Lemaitre & Hoffmann, 2007).”
Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. (2009, background): “To date, the role of the JAK-STAT pathway in immunity has been limited to antiviral defense and stress response (Lemaitre and Hoffmann, 2007).”
Environmentally sustainable pest control options for Drosophila suzukii (2018, background): “In contrast, D. melanogaster is susceptible to numerous viruses and is a powerful model to study host- pathogen interactions (Lemaitre & Hoffmann, 2007).”
The Drosophila Toll Signaling Pathway (2011, background): “It is clear that the Drosophila Toll pathway plays a key role in Gram-positive bacterial and fungal infections (80).”
The Bacterial Symbiont Wolbachia Induces Resistance to RNA Viral Infections in Drosophila melanogaster (2008, neutral): “and bacteria are increasingly well known [35].”