Viruses and interferon: a fight for supremacy

By Michael G. Katze, Yupeng He, M. Gale. Nature reviews. Immunology, 2002

1,475 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology, Immunology

View Paper: https://www.semanticscholar.org/paper/bb0e064812fdad9229173a1f5d5ffb2a6a3e0cc2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. R. Medzhitov
2. R. Flavell
3. Eileen M. Foy
4. A. Iwasaki
5. Shizuo Akira
6. Kui Li
7. J. Hoofnagle
8. Jacques Banchereau

In Hepatology

1. Eileen M. Foy
2. R. Medzhitov
3. J. Hoofnagle
4. M. Gale
5. Shizuo Akira

In Immunology

1. Shizuo Akira
2. R. Medzhitov
3. Jacques Banchereau
4. Taro Kawai
5. O. Takeuchi
6. A. Iwasaki
7. M. Gale
8. Mitsutoshi Yoneyama

Citations in the corpus

• Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I (2005, background): “The specificity of this assay for dsRNA binding proteins was confirmed by the recovery of endogenous PKR, a known dsRNA binding protein (12), but not endogenous actin.”
• Toll-like receptor control of the adaptive immune responses (2004, background): “The function of type I interferons in adaptive immunity The type I interferon family consists of IFN-α, IFN-β, IFN-ω and IFN-&lambda”
• Viral infection switches non-plasmacytoid dendritic cells into high interferon producers (2003, background): “The viral components leading to IFN-I induction remain largely unidentifie”
• Evasion of intracellular host defence by hepatitis C virus (2005, background): “To replicate and spread successfully, viruses direct various strategies to evade host defence”
• Mechanism of action of interferon and ribavirin in treatment of hepatitis C (2005, background): “These studies highlight the complexity of teasing out the actions of HCV proteins on the often-multitiered IFN signalling pathways during acute and chronic infection, and during therapy of hepatitis”
• The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. (2008, background): “Viral infection triggers a series of signaling events that lead to induction of type I interferons (IFNs), including IFN-b and IFN-a family cytokines (Akira et al., 2006; Fitzgerald et al., 2003; Hiscott, 2007; Honda et al., 2006; Katze et al., 2002).”
• The Airway Epithelium: Soldier in the Fight against Respiratory Viruses (2011, background): “They bind to the type I IFN receptor complex (IFNAR1 and -2) and induce a range of different genes encoding proteins that selectively interfere with virus replication, protein synthesis, or protein trafficking (16, 139, 245).”