Evasion of intracellular host defence by hepatitis C virus

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Vaccine Adjuvants: Putting Innate Immunity to Work (2010, background): “…be necessary to generate potent and perhaps multifunctional T cell responses in patients who respond poorly to the relevant tumor or viral Immunity 33, October 29, 2010 ª2010 Elsevier Inc. 493 antigens as a result of multiple layers of immune regulation (Gale and Foy, 2005; Rosenberg et al., 2004).”
The interferon response circuit: Induction and suppression by pathogenic viruses (2005, background): “Comprehensive reviews have recently dealt with these issues (Basler and Garcia-Sastre, 2002; Conzel- mann, 2005; Gale and Foy, 2005; Hengel et al., 2005; Weber et al., 2004).”
Hepatocellular carcinoma pathogenesis: from genes to environment (2006, background): “Various other immune-evasion mechanisms are used by HCV proteins, as detailed elsewher”
Interferon signaling and treatment outcome in chronic hepatitis C (2008, background): “The capacity of HCV to interfere with the IFN pathway at many different levels is a likely mechanism underlying HCV success to establish a chronic infection (2).”