Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial.

By F. Thies, J. Garry, P. Yaqoob, K. Rerkasem, Jennifer A. Williams, C. Shearman, P. Gallagher, P. Calder, R. Grimble. The Lancet, 2003

818 citations recorded by the source corpus.

Subfields: Biochemistry, Cancer Research, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/b98491b9820e456746460c742bc32eb4741b5678

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In Biochemistry

In Cancer Research

P. Calder

In Nutrition and Dietetics

Citations in the corpus

Omega-3 fatty acids and inflammatory processes: from molecules to man. (2017, neutral): “A study in patients awaiting surgical removal of plaques from the carotid artery showed that EPA and DHA are incorporated from n-3 PUFA supplements into advanced atherosclerotic plaques and that this incorporation is associated with fewer macrophages in the plaque and with structural changes consist”
Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021 (2021, neutral): “Thus, omega- 581 3 PUFAs may directly target atherosclerotic plaques in patients who already have ad- 582 vanced CVD, as suggested by earlier studies in mice [188] and humans [189,190].”
Omega-3 Fatty Acids and Inflammatory Processes (2010, background): “rupture [115], which again has an inflammatory component [112,116].”
The Omega-3 Index: a new risk factor for death from coronary heart disease? (2004, methodology): “In addition, EPA + DHA may enhance plaque stability [24], and may be antiatherosclerotic via a variety of other mechanisms [25].”
Omega-3 polyunsaturated fatty acids and cardiovascular diseases. (2009, background): “In addition to mechanisms discussed above, !-3 PUFA produces vasodilation, reduces blood pressure (31,66), improves arterial and endothelial function (67), and reduces platelet aggregation (68).”
Functional Roles of Fatty Acids and Their Effects on Human Health. (2015, background): “The third mechanism is the well-documented anti-inflammatory effect of EPA and DHA, which would serve to stabilize atherosclerotic plaques, preventing their rupture.(143,144) EPA and DHA exert a range of biological activities that may influence tumor cell proliferation and viability; for example, DH”