Reduction of Inflammatory Cytokine Concentrations and Improvement of Endothelial Functions in Obese Women After Weight Loss Over One Year

By P. Ziccardi, F. Nappo, G. Giugliano, K. Esposito, R. Marfella, M. Cioffi, F. D’Andrea, A. Molinari, D. Giugliano. Circulation, 2002

1,086 citations recorded by the source corpus.

Subfields: Epidemiology, Oncology, Physiology

View Paper: https://www.semanticscholar.org/paper/b64394cb15083f1ca8b2c8ada8e5ab74a3e006da

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. P. Calder
2. I. Azevedo
3. Mihai G. Netea
4. R. Monteiro
5. R. Goldberg
6. J. Keaney

In Oncology

1. P. Calder

In Physiology

1. P. Calder
2. I. Azevedo
3. R. Monteiro
4. C. Mantzoros
5. R. Goldberg
6. J. Keaney
7. Karine Clément
8. L. Galland

Citations in the corpus

• Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. (2009, background): “Importantly, weight reduction decreases levels of CRP, IL-6, and TNF , (72) and lowers sICAM-1, sVCAM-1, and P-selectin (73).”
• The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. (2007, background): “Later data have shown that TNF-a is also expressed in human adipose tissue and that its plasma concentration in obese subjects is decreased after weight loss (94, 95).”
• Effect of a mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. (2004, background): “Waist circumference, cm 92 (9) 93 (10) .”
• Obesity and cancer risk: Emerging biological mechanisms and perspectives. (2019, background): “Ziccardi et al showed an attenuation of endothelial dysfunction in women that lost weight [114].”
• The effects of diet on inflammation: emphasis on the metabolic syndrome. (2006, neutral): “educe inflammation and improve endothelial function (46).”
• The clinical implications of endothelial dysfunction. (2003, background): “In obese women, a yearlong program of low fat diet and exercise reduced plasma levels of tumor necrosis factoralpha, interleukin-6, soluble ICAM-1, and soluble vascular cell adhesion molecule-1 (VCAM-1) (52).”
• Endothelial Dysfunction: Cardiovascular Risk Factors, Therapy, and Outcome (2005, neutral): “…of caloric restriction (800 kcal/day), achieving 9% weight loss (Ferri et al 1999), and circulating levels of inflammatory cytokines were similarly reduced in obese women after a 1-year multidisciplinary weight loss program which achieved at least 10% reduction in weight (Ziccardi et al 2002).”
• Chronic Inflammation in Obesity and the Metabolic Syndrome (2010, result): “In good agreement with this interpretation of things, weight loss of obese patients is repeatedly verified to be associated with a decrease of inflammation biomarkers [17–21] accompanied by improvement of metabolic parameters, namely, insulin sensitivity [22–26].”