Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications.

By R. Goldberg. Journal of Clinical Endocrinology and Metabolism, 2009

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The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing (2021, background): “Diabetic microangiopathy and macroangiopathy are the combined result of irreversible complex nonenzymatic glycation, elevated oxidative stress and inflammation, and endothelial dysfunction and hypercoagulability state [58].”
Molecular Mechanisms Linking Oxidative Stress and Diabetes Mellitus (2020, background): “The inflammatory response is one of the main underlying molecular mechanisms involved in the pathophysiology of insulin resistance, DM, and its related complications [53, 103, 104].”
Pathophysiology of Type 2 Diabetes Mellitus (2020, background): “This balance is altered in T2DM leading to alteration of the physicochemical properties of the vascular wall via endothelial dysfunction, oxidative stress, platelet hyperreactivity, and inflammation [240,241].”