The impact of the extracellular matrix on inflammation

By L. Sorokin. Nature reviews. Immunology, 2010

895 citations recorded by the source corpus.

Subfields: Cancer Research, Cell Biology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/b6060404aef4df812d727aaf614bc9af3a3fec39

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. A. Prat
2. Li Yang
3. Yi Zhang
4. R. Daneman

In Cell Biology

1. A. Prat
2. Li Yang
3. Yi Zhang
4. R. Daneman

In Immunology and Allergy

1. A. Prat
2. Li Yang
3. Yi Zhang
4. R. Daneman

Citations in the corpus

• Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size (2013, neutral): “189,190 193 Amino acid sequence-Arg-Gly-Asp-(RGD)”
• The secretion profile of mesenchymal stem cells and potential applications in treating human diseases (2022, background): “During the process of tissue injury and repair, chronic inflammation is always associated with aberrant ECM deposition, and the fragments of ECM may activate immune cells and support their survival during the tissue-remodeling processes.(170) The crucial role of the ECM for adhesion and migration of”
• Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives (2021, background): “The CAFremodeled ECM protein network serves as a physical barrier for immune cells, especially T lymphocytes, thus inhibiting their recruitment into cancer sites and subsequently reducing their opportunities to participate in the immune response in the TME [279, 280].”
• Tumor-associated macrophages: from basic research to clinical application (2017, background): “Tumor-derived extracellular matrix (ECM) components, including biglycan and hyaluronan, are potentially important factors in directing TAM polarization via TLR2 and TLR4 [33].”
• The blood-brain barrier. (2015, background): “The vascular tube is surrounded by two BMs, the inner vascular BM and the outer parenchymal BM, also called the vascular glia limitans perivascularis (Del Zoppo et al. 2006; Sorokin 2010).”
• The blood–brain barrier in health and disease: Important unanswered questions (2020, background): “Additionally, several imaging studies have found evidence of a leakier BBB in AD patients and propose BBB dysfunction as an early biomarker of AD (Starr et al., 2009; Montagne et al., 2015; van de Haar et al., 2016; Nation et al., 2019).”
• Extracellular matrix: a dynamic niche component during cancer progression (2012, neutral): “mediated adhesion complex assembly and activate T cells (Ashkar et al., 2000; Adler et al., 2001; Hur et al., 2007; Sorokin, 2010).”
• The extracellular matrix modulates the hallmarks of cancer (2014, neutral): “Similarly, macrophages require expression of the collagen receptor DDR1 to infiltrate atheroschlerotic plaques [116], whereas the ECM protein SPARC significantly inhibits macrophage infiltration [98].”