The blood–brain barrier in health and disease: Important unanswered questions

By C. Profaci, Roeben N. Munji, Robert S. Pulido, R. Daneman. Journal of Experimental Medicine, 2020

602 citations recorded by the source corpus.

The blood vessels of the central nervous system tightly control the movement of ions, molecules, and cells between the blood and tissue. This “blood–brain barrier” is vital for neural homeostasis and protection. This review discusses current knowledge of the blood–brain barrier, emphasizing key unanswered questions.

Subfields: Neurology, Oncology, Physiology

View Paper: https://www.semanticscholar.org/paper/314258500ba2033b3643422f95db18694c2d9b10