Ribo-gnome: The Big World of Small RNAs

By Phillip D. Zamore, B. Haley. Science, 2005

1,323 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/b594d7f149decef0209cb43179a8730cf39cfd82

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Carlo Maria Croce
2. George A. Calin
3. V. Narry Kim
4. Marilena V. Iorio
5. John S. Mattick
6. T. Rana
7. Young‐Kook Kim
8. Gregory J. Hannon

In Plant Science

1. John S. Mattick
2. V. Narry Kim
3. Gregory J. Hannon
4. T. Rana
5. C. Mello
6. Lin He
7. David M. Sabatini
8. George A. Calin

Citations in the corpus

• Illuminating the silence: understanding the structure and function of small RNAs (2007, background): “Upon recognizing complementary mRNA, activated siRISC forms an effector complex with the target mRN”
• A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. (2007, background): “The effects that are induced by Argonaute proteins include the induction of histone and DNA methylation, deletion of DNA sequences, mRNA breakdown, and inhibition of translation; the specificity of these processes is in part determined by the identity of the Argonaute protein involved (Zamore and Ha”
• Human tRNA-derived small RNAs in the global regulation of RNA silencing. (2010, background): “…(Hock et al. 2007), no obvious changes in the small RNA profiles were observed following transient overexpression of a FLAG-tagged Argonaute 2 (Zhang et al. 2009), and no gross differences were noted in small RNA immunoprecipitations with antibodies against endogenous Argonautes when compared…”
• Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. (2005, neutral): “miRNAs are small noncoding RNAs that repress gene expression by recruiting effector complexes (miRNPs) to miRNA complementary sites on mRNAs (Bartel, 2004; Zamore and Haley, 2005 ).”
• The role of PACT in the RNA silencing pathway (2006, background): “The small RNAs are loaded onto the effector complex, known as the RNA-induced silencing complex (RISC) (Filipowicz, 2005; Sontheimer, 2005; Tomari and Zamore, 2005; Zamore and Haley, 2005).”
• The ancient Virus World and evolution of cells (2006, background): “The ubiquity of both temperate selfish elements and RNAi-based defense systems [79-81] in all life forms is compatible with the origin of these phenomena at a very early stage of evolution.”
• Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process (2008, background): “miRNAs constitute a group of endogenous small, non coding RNAs of approximately 22 nucleotides in length that exert a posttranscriptional effect on gene expression [45,46].”
• MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer (2008, background): “MicroRNAs (miRNAs) have been discovered as naturally occuring non-coding RNAs, controlling gene expression via specific sites at the 30-UTR of target-mRNAs, causing translational repression or degradation (Berezikov et al., 2005; Pillai et al., 2005; Zamore and Haley, 2005).”