A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.
By S. Houwing, L. Kamminga, Eugene Berezikov, Daniela Cronembold, Angélique Girard, H. Elst, D. Filippov, Heiko Blaser, E. Raz, C. Moens and 4 more. Cell, 2007
1,124 citations recorded by the source corpus.
Subfields: Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/b234fc5906e7eeccff688634a0e39d13efa05a5e
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Gregory J. Hannon
- Alexei Aravin
- Eric S. Lander
- Manolis Kellis
- J. Brennecke
- Hiroyuki Sasaki
- Ravi Sachidanandam
- Michael F. Lin
In Plant Science
- Gregory J. Hannon
- Ravi Sachidanandam
- J. Brennecke
- Alexei Aravin
- Dubravka Pezic
- D. Bourc’his
- Olena Morozova
- E. Li
Citations in the corpus
- Applications of next-generation sequencing technologies in functional genomics. (2008, background): “required for germ cell development in mammals and other species [86–88].”
- Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary (2009, background): “Signatures of the ping-pong cycle are conserved throughout animals, suggesting that it is a fundamental property of the piRNA pathway (Aravin et al., 2007b; Houwing et al., 2007; Murchison et al., 2008).”
- DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. (2008, positive): “…RNAs against transposon sequences have been cloned in germlines, and the loss of Piwi family gene expression causes downregulation of these small RNAs in Drosophila, zebrafish, and mice (Saito et al. 2006; Aravin et al. 2007; Brennecke et al. 2007; Gunawardane et al. 2007; Houwing et al. 2007).”
- Distinguishing protein-coding and noncoding genes in the human genome (2007, background): “The piRNAs of platypus adult testis have features of both fish and eutherian piRNA systems (Houwing et al. 2007) and suggest that mammalian piRNA clusters that are expressed late in germ cell development may have progressively lost repeat content as they acquired novel functions (Aravin et al.…”
- Spermatogenesis in fish. (2010, background): “the Argonaut family of proteins result in complete germ cell loss as well (Houwing et al., 2008; Houwing et al., 2007).”
- Oogenesis in teleosts: how eggs are formed. (2010, neutral): “are components of the ‘‘nuage” germ-line structure (Houwing et al., 2007).”
- Argonaute proteins: key players in RNA silencing (2008, background): “and are required to silence mobile elements and thereby maintain genome integrit”