Molecular and cellular mechanisms of cardiac arrhythmias.

By M. Keating, Michael Sanguinetti. Cell, 2001

1,004 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b44c77c4bc0ebb30c4cae43e6b52e5a309392202

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In Cardiology and Cardiovascular Medicine

In Molecular Biology

Citations in the corpus

Overview of the voltage-gated sodium channel family (2003, background): “and Brugada syndrome [45], both of which lead to an increased risk of ventricular arrhythmias.”
Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons. (2004, background): “, 2003), suggesting the cardiac-specific KCNH2 potassium channel subunit as a possible molecular target (Keating and Sanguinetti, 2001; Mitcheson et al., 2000).”
Voltage‐gated sodium channels at 60: structure, function and pathophysiology (2012, background): “5 channels cause long QT syndrome by impairing sodium channel inactivation (Keating & Sanguinetti, 2001).”
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. (2004, neutral): “2 mis- Keating and Sanguinetti, 2001).”
Molecular physiology of cardiac repolarization. (2005, background): “3A) and linked to Brugada syndrome and to conduction defects, in addition to LQT3 (23, 36, 51, 60, 93, 102, 105, 204, 253, 422, 519, 525, 540).”
Discovering Endophenotypes for Major Depression (2004, methodology): “Finally, using QT interval elongation as endophenotype allowed for successful genetic linkage studies (Keating et al, 1991; Keating and Sanguinetti, 2001).”
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. (2001, background): “The occurrence of both periodic paralysis and long QT tions in voltage-gated K1 and Na1 channels (Keating and Sanguinetti, 2001).”
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death (2003, background): “jpg" NDATA ITEM> ]> Mutations in ion channels involved in the generation and termination of action potentials constitute a family of molecular defects that underlie fatal cardiac arrhythmias in inherited long-QT syndrom”
The endophenotype concept in psychiatry: etymology and strategic intentions. (2003, methodology): “Manifestations of long QT syndrome include syncope, ventricle arrhythmias, and sudden death (63).”