Cutting Edge: Long-Term B Cell Memory in Humans after Smallpox Vaccination 1
By Shane Crotty, Philip L. Felgner, H. Davies, John Glidewell, L. Villarreal, Rafi Ahmed. Journal of Immunology, 2003
716 citations recorded by the source corpus.
Subfields: Immunology, Infectious Diseases
View Paper: https://www.semanticscholar.org/paper/adf32586f4a969643198439c08733223b0989019
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In Immunology
- Bali Pulendran
- J. Wherry
- W. Nicholas Haining
- Rafi Ahmed
- F. Krammer
- A. García‐Sastre
- P. Palese
- Steven G. Deeks
In Infectious Diseases
Citations in the corpus
- Redefining chronic viral infection. (2009, neutral): “, 1997) and are responsible for the prolonged maintenance of antiviral antibodies observed in humans for decades in the absence of viral reinfection (Hammarlund et al., 2003; Crotty et al., 2003) Although there is considerably more known about exhaustion and dysfunction of T cells during chronic vir”
- Systems Biology of Seasonal Influenza Vaccination in Humans (2011, methodology): “Direct ELISPOT to enumerate both total and influenza specific IgG, IgM and IgA plasmablasts present in fresh PBMC samples were essentially done as previously described 15,53 .”
- Memory CD8 T-Cell Differentiation during Viral Infection (2004, background): “Acute infections with viruses such as influenza virus and vaccinia virus do not result in viral persistence and induce functional memory T cells that develop and persist in the absence of antigen (30, 31, 49, 68, 123).”
- Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans (2014, methodology): “Direct ELISPOT to enumerate total and HA specific plasmablasts were performed as previously described (39).”
- Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T-cells (2012, result): “The essentially stable persistence of CD4ζ CAR T cells that we have observed is similar to the 14 year half life reported for vaccinia-specific human T cells (33).”
- Translating innate immunity into immunological memory: implications for vaccine development. (2006, neutral): “…vectors, such as the vaccinia virus, with which billions of individuals were immunized during the smallpox eradication campaign in the 1970s (Crotty et al., 2003), infects DCs, (paradoxically) inhibits DC activation, and causes extensive cell death, resulting in crosspresentation of…”