Human Embryonic Stem Cells Develop Into Multiple Types of Cardiac Myocytes: Action Potential Characterization
By Jia-Qiang He, Yue Ma, Youngsook Lee, James A. Thomson, T. Kamp. Circulation Research, 2003
818 citations recorded by the source corpus.
Subfields: Biomedical Engineering, Cellular and Molecular Neuroscience, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/ad421e55153d9e844c2be6db43d2a450076c3b73
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In Biomedical Engineering
In Cellular and Molecular Neuroscience
In Molecular Biology
- G. Keller
- Charles E. Murry
- M. Laflamme
- M. Reth
- James A. Thomson
- Nikolaos G. Frangogiannis
- H. Ruskoaho
- Virpi Talman
Citations in the corpus
- Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages (2005, background): “Repeated impalements of individual QD 655 -marked differentiated progenitors revealed reproducible action potentials with distinct morphologies, nodal-like and atrial-like, supporting the concept that these cells are able to differentiate into a distinct subset of cardiac lineages, including conduct”
- High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. (2011, background): “Differentiation of hiPSCs or hESCs into cardiomyocytes can be achieved using embryoid body and various directed differentiation approaches (13, 23, 48, 52).”
- Regenerating the heart (2005, background): “As with their mouse counterparts, human ES cell–derived cardiomyocytes show the expected molecular, structural, electrophysiologic and contractile properties of nascent embryonic myocardiu”
- Embryonic stem cells (2004, neutral): “…et al. 2003), strategies to select out the appropriate cell type from the differentiated population (Muller et al. 2000), and cardiomyocytes are now being generated from human ES cells based on protocols optimized for murine ES cells (Kehat et al. 2001; He et al. 2003; Mummery et al. 2003).”
- Embryonic stem cell differentiation: emergence of a new era in biology and medicine. (2005, background): “Although the hES-cellderived cardiomyocytes do not undergo maturation to the stage of adult cardiomyocytes, cells with electrical properties of nodal, atrial, and ventricular cells have been identified (He et al. 2003).”
- Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. (2008, background): “Catecholamines enhance cardiomyocyte beating rate and contractility (He et al., 2003; Xu et al., 2002), indicating the presence of intact adrenergic signal transduction pathways and a functional sarcoplasmic reticulum that regulates contraction through calcium-induced calcium ion release (Liu et al.”