Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages
By K. Laugwitz, A. Moretti, J. Lam, P. Gruber, Yinhong Chen, S. Woodard, Li-Zhu Lin, Chen-Leng Cai, M. Lu, M. Reth and 4 more. Nature, 2005
1,255 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology, Surgery
View Paper: https://www.semanticscholar.org/paper/7adfa33a009bd0b4c428ae48fd7c5ec3ffaf12e5
How researchers see this paper
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In Cardiology and Cardiovascular Medicine
In Molecular Biology
- Deepak Srivastava
- B. Bruneau
- Stefanie Dimmeler
- A. Zeiher
- V. Vedantham
- M. Schneider
- Margaret E. Buckingham
Citations in the corpus
- Unchain my heart: the scientific foundations of cardiac repair. (2005, background): “have been identified on the basis of persistent expression of a LIM-homeodomain transcription factor, Isl1, especially in the atria, right ventricle, and outflow tract — regions where Isl1 is most prevalently expressed during cardiac organogenesis (43).”
- Building the mammalian heart from two sources of myocardial cells (2005, background): “Identification of novel heart fields In addition to growth of myocardial cells within the cardiac tube (and possibly of rare undifferentiated cell”
- Making or breaking the heart: from lineage determination to morphogenesis. (2006, background): “Interestingly, Isl1-positive cells mark niches of undifferentiated cardiac progenitor cells in the postnatal heart (Laugwitz et al., 2005), suggesting that understanding the regulation of SHF-derived progenitor pools may be useful in developing approaches for cardiac repair (discussed below).”
- Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors (2010, background): “This conclusion was supported by the absence of Isl1-Cre-YFP or Mesp1-Cre-YFP activation during the process of reprogramming, which would havemarked any cells that transiently expressed Isl1 or Mesp1 (Laugwitz et al., 2005; Saga et al., 1999).”
- A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. (2006, neutral): “To assess epicardial activity during regeneration, we followed expression of raldh2 and tbx18, genes expressed in the developing embryonic epicardium (Moss et al., 1998; Kraus et al., 2001 ).”