Neuroadaptation: Incubation of cocaine craving after withdrawal

By Jeffrey W Grimm, B. Hope, R. Wise, Y. Shaham. Nature, 2001

969 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/ab8cb5389b2cf91761125d630c413c78ee35f67b

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Citations in the corpus

Psychomotor Stimulant Addiction: A Neural Systems Perspective (2002, background): “cocaine (Grimm et al., 2001), suggesting that neuroadaptations to”
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure (2006, background): “In fact, in the case of cocaine cues, reinstatement responding increases over the first 2 months of withdrawal from the drug, a phenomenon termed INCUBATION OF COCAINE CRAVING (Grimm et al. 2001; Lu et al. 2004b).”
Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling (2011, background): “An additional drug-induced synaptic adaptation in the NAc occurs during protracted (6–7 weeks) withdrawal from cocaine self-administration, a period that is associated with an increase in cue-induced cocaine seeking (a model for craving) (Grimm et al., 2001).”
The reinstatement model of drug relapse: history, methodology and major findings (2003, background): “Both cue-induced reinstatement (Grimm et al. 2001) and footshock-induced reinstatement (Shalev et al. 2001) were maximal at time points that are well beyond the acute withdrawal phase and, surprisingly, the least amount of lever pressing occurred on day 1 of withdrawal from cocaine (Fig.”
Neurobiology of Relapse to Heroin and Cocaine Seeking: A Review (2002, background): “Data are from Tran-Nguyen et al., 1998, reprinted ©1998 with permission from Elsevier Science; Grimm et al., 2001, reprinted ©2001 with permission from Nature; and Shalev et al., 2001, reprinted ©2001 with permission from Springer-Verlag. drugs of abuse act on brain systems underlying natural reward”
Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. (2008, background): “…and then being forced to abstain, animals often persist in unrewarded operant responding (i.e., resistance to response extinction), and increase their responding over time for cues previously associated with the drug (i.e., incubation) (Bienkowski et al., 2004; Grimm et al., 2001; Lu et al., 2004).”
Brain circuitry and the reinstatement of cocaine-seeking behavior (2003, background): “Moreover, it is clear that the intensity of reinstatement augments with increasing duration of the extinction/withdrawal period (Tran-Nguyen et al. 1998; Grimm et al. 2001).”
Neural substrates of smoking cue reactivity: A meta-analysis of fMRI studies (2011, neutral): “…attribution of excessive incentive salience to drug cues (Robinson & Berridge, 2003), especially under conditions of deprivation (Drummond, 2000; Grimm et al., 2001; Robinson & Berridge, 2008), which leads to a perceptual bias toward these cues (Everitt & Robbins, 2005; Koob & LeMoal, 2001;…”
Sensitization of Midbrain Dopamine Neuron Reactivity Promotes the Pursuit of Amphetamine (2002, neutral): “…1991) as well as nonpharmacological events (Piazza and Le Moal, 1996), may thus underlie the propensity of individuals to engage in drug-taking behavior as well as their liability for relapse, even after prolonged abstinence (De Vries et al., 1998; Tran-Nguyen et al., 1998; Grimm et al., 2001).”
The neural basis of addiction: a pathology of motivation and choice. (2005, background): “It is interesting that, like the locomotor sensitization and drug-seeking behaviors associated with addiction (85, 86), changes in protein content and/or function in this category often become greater with increasing periods of withdrawal (87–89).”
Brain reward circuitry: insights from unsensed incentives. (2002, background): “Finally, the animal might learn the sound or a few months (Grimm et al., 2001) after the last expo- of the waterfall that is near the visible landmarks and sure to drug.”