Molecular evolution of a microRNA cluster.

By Andrea Tanzer, Peter F. Stadler. Journal of Molecular Biology, 2004

677 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ab4ecab99dc9fbeecc006dfa0aa99787771d3dbd

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Citations in the corpus

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation (2018, background): “Sometimes miRNAs are transcribed as one long transcript called clusters, which may have similar seed regions, and in which case they are considered a family (25).”
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. (2008, background): “miR-20a is part of the miR-17-92 polycistronic microRNA cluster.(35) Overexpress ion of this c luster enhances cell proliferation in vitro(36) and accelerates tumor formation in animal models.”
miRGen: a database for the study of animal microRNA genomic organization and function (2006, background): “Furthermore, these pri-miRNAs often contain several miRNAs (11).”
MicroRNA functions in animal development and human disease (2005, background): “For the mir-17 cluster and the microRNAs in the HOX gene cluster, an evolutionary analysis has been reported (Tanzer et al., 2005; Tanzer and Stadler, 2004).”
microRNAs in cancer (2013, background): “For instance, the miR-17/92 cluster produces a single polycistronic precursor that matures into six individual miRNAs (7), which are categorized into four miRNA families: miR-17 (miR-17 and miR-20), miR-18, miR-19 (miR-19a and miR-19b), and miR-92.”
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes (2008, background): “This genomic organization is highly conserved in all vertebrates from which complete genome sequences are availabl”
The evolution of gene regulation by transcription factors and microRNAs (2007, background): “Several detailed studies in plants [52] and animals [53, 54 ] have shown that miRNA families can expand by the same processes of tandem, segmental and whole-genome duplication as protein-coding genes.”
MicroRNA control in the immune system: basic principles. (2009, background): “This genomic organization is highly conserved in all vertebrates from which complete genome sequences are available (Tanzer and Stadler, 2004).”
Clustering and conservation patterns of human microRNAs (2005, background): “However, larger clusters were also identified, such as the human hsa-miR-17 cluster composed of six members (10,11), which is also conserved in other mammals (13), or the Drosophila melanogaster cluster of eight miRNA genes (12).”
Global and Local Architecture of the Mammalian microRNA–Transcription Factor Regulatory Network (2007, background): “miR-93 cluster members are also homologous to two other genomic miR clusters, one of which is miR cluster 17/92 [41].”
Computational prediction of miRNAs in Arabidopsis thaliana. (2005, background): “In animal systems, the presence of tandem arrays of miRNA genes has been previously reported (Tanzer and Stadler 2004).”
Conservation and divergence of plant microRNA genes. (2006, background): “Animal genomes contain clusters of miRNAs (Altuvia et al., 2005; Seitz et al., 2004; Tanzer and Stadler, 2004), but plant miRNA clusters have not been frequently observed.”
Specialization and evolution of endogenous small RNA pathways (2007, background): “It is clear that animal miRNA families, such as the human mir17 cluster and the miRNAs in the Hox gene cluster, have expanded by the duplication of individual genes and gene cluster”
Genomic Organization, Differential Expression, and Interaction of SQUAMOSA Promoter-Binding-Like Transcription Factors and microRNA156 in Rice1[W] (2006, background): “AK110797), which was similar to the phenomenon that many miRNAs in animals are encoded by a polycistronic transcript through an initial phase of local duplication (Tanzer and Stadler, 2004).”