Distinctive chromatin in human sperm packages genes for embryo development
By Jahnvi Pflueger. 2009
1,055 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/aa8d53902cfc5b04af93e702efbba205f6bf294d
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Citations in the corpus
- Understanding transgenerational epigenetic inheritance via the gametes in mammals (2012, background): “However, we now know that ~1–2% of the haploid genome in mice and ~4% of that in humans remains packaged into nucleosomes in sper”
- Histone variants — ancient wrap artists of the epigenome (2010, unknown): “Z nucleosomal DNA is enriched in pericentric heterochromatin 113 .”
- Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa (2010, background): “Despite such major remodeling, histones have been reported to reside at specific sequences in human and mouse spermatozo”
- Epigenetics and the environment: emerging patterns and implications (2012, background): “, there is a persistence of histones and associated modifications in mature sper”
- Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (2010, background): “Third, chromatin structure has been proposed to carry epigenetic information, as sperm are largely devoid of histone proteins but retain them at a subset of developmentally important loci (Arpanahi et al., 2009; Brykczynska et al., 2010; Chong et al., 2007; Hammoud et al., 2009).”
- Targets and dynamics of promoter DNA methylation during early mouse development (2010, unknown): “Alternative mechanisms for epigenetic inheritance could involve RNAs or modified histones that transmit information from gametes to early embryo”
- Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage (2010, background): “Other factors that may contribute to abnormal development before EGA include inherited genetic mutations, aneuploidy, environmental insult to germ cells, events during fertilization and sperm-related factor”
- Missing heritability and strategies for finding the underlying causes of complex disease (2010, background): “The obvious molecular mechanisms for epigenetic inheritance are DNA methylation and histone modification”