Targets and dynamics of promoter DNA methylation during early mouse development
By Julie Borgel, S. Guibert, Yufeng Li, H. Chiba, Dirk Schübeler, Hiroyuki Sasaki, T. Forné, Michael Weber. Nature Genetics, 2010
600 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/5bee5a1c949d4641aed96fa0cafb5e019eff0b1f
How researchers see this paper
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In Molecular Biology
- Wolf Reik
- W. Dean
- Jörn Walter
- Alexander Meissner
- Felix Krueger
- Fátima Santos
- Simon R. Andrews
- Hao Wu
Citations in the corpus
- A unique regulatory phase of DNA methylation in the early mammalian embryo (2012, background): “After specification of the ICM, the embryo implants into the uterine lining in concert with gastrulation, which is accompanied by a global remethylation of the genome that is believed to contribute to lineage restriction and the loss of cellular potency 12,13 .”
- The role of mutations in epigenetic regulators in myeloid malignancies (2012, background): “TET2 and DNA hydroxymethylation The TET family of proteins was first identified with the cloning of TET1 as a fusion partner of MLL in patients with t(10;11)(q22;q23) AML23.”
- DNA methylation: a historical perspective. (2022, unknown): “These studies, together with previous work [210], further highlighted that most endogenous promoters are not primarily regulated by methylation and that unmethylated promoters are enriched for H3K4 methylation [211].”
- DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos (2014, background): “, at pluripotency gene promoters, where DNA methylation is thought to act as a safety mechanism to reinforce silencing during differentiation, as well as at promoters of germ cell-specific genes (Maatouk et al. 2006; Weber et al. 2007; Farthing et al. 2008; Meissner et al. 2008; Borgel et al. 2010).”
- The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells (2012, background): “…the inner cell mass are globally hypomethylated, as a result of epigenetic reprogramming during preimplantation development, but upon implantation rapid de novo methylation occurs primarily in the epiblast (Howlett and Reik, 1991; Santos et al., 2002; Borgel et al., 2010; Smith et al., 2012).”
- Methylation multiplicity and its clinical values in cancer (2021, unknown): “15).”