Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

By Urszula Brykczynska, Mizue Hisano, S. Erkek, L. Ramos, E. Oakeley, Tim C. Roloff, C. Beisel, Dirk Schübeler, Michael B. Stadler, Antoine H. F. M. Peters. Nature Structural &Molecular Biology, 2010

667 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b255c486be3fe9737cfe7c65cf27c25324ce4f42

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Citations in the corpus

Transgenerational Epigenetic Inheritance: myths and mechanisms (2014, neutral): “Furthermore, most paternal RNAs are thought to be degraded shortly after fertilization, and although some histones may persist in sperm chromatin (Brykczynska et al., 2010; Hammoud et al., 2009), most are rapidly replaced upon fertilization.”
Understanding transgenerational epigenetic inheritance via the gametes in mammals (2012, background): “However, we now know that ~1–2% of the haploid genome in mice and ~4% of that in humans remains packaged into nucleosomes in sper”
Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (2010, background): “Third, chromatin structure has been proposed to carry epigenetic information, as sperm are largely devoid of histone proteins but retain them at a subset of developmentally important loci (Arpanahi et al., 2009; Brykczynska et al., 2010; Chong et al., 2007; Hammoud et al., 2009).”
Epigenetics and the environment: emerging patterns and implications (2012, background): “, there is a persistence of histones and associated modifications in mature sper”