Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention
By S. Padayatty, A. Katz, Yaohui Wang, P. Eck, O. Kwon, Je-Hyuk Lee, Shenglin Chen, C. Corpe, Anandi Dutta, S. Dutta and 1 more. Journal of the American College of Nutrition, 2003
2,054 citations recorded by the source corpus.
Subfields: Biochemistry, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/9ab6733d21f78c6af3d54f34058d3d6d4f6f1b94
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- S. Padayatty
- Qi Chen
- M. Levine
- M. Espey
- Andrew Y. Sun
- Chaya Pooput
- K. Kirk
- M. Krishna
Citations in the corpus
- Vitamin C physiology: the known and the unknown and Goldilocks (2016, neutral): “…Promote iron absorption (Hallberg et al., 1987) Antioxidant Site Action Cells Regulate gene expression and mRNA translation, prevent oxidant damage to DNA and intracellular proteins (Hitomi & Tsukagoshi, 1996, Toth et al., 1995, Padayatty et al., 2003, Qiao & May, 2011, Sram et al., 2012).”
- Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice (2008, background): “An additional viewpoint is that ascorbate serves as an antioxidant and increased intake from either foods or dietary supplements might promote good health (1).”
- Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. (2014, background): “It is synthesized from glucose in the liver of most mammalian species, but not by humans and therefore must be ingested to avoid scurvy, a potentially lethal condition (216).”
- Reactive Oxygen Species Signaling and Oxidative Stress: Transcriptional Regulation and Evolution (2024, background): “The antioxidative properties of vitamin C are primarily attributed to its ability to readily donate electrons, stabilizing and thereby quenching the damaging oxidative reactions initiated by ROS [24].”
- Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use (2004, background): “Because differences in plasma concentrations from supplements and from food intake are not large, supplements would be expected to confer little additional benefit, a finding supported by available evidence (16, 17).”
- Oxidative Stress in Aging Human Skin (2015, background): “This radical can either be reduced back or can react further to dehydroascorbic acid [119].”