Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis
By S. Matsuyama, J. Llopis, Q. Deveraux, Roger Tsien, John Calvin Reed. Nature Cell Biology, 2000
763 citations recorded by the source corpus.
Subfields: Epidemiology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/9815ecc83a14f1ef8a4b1afa37a59c96db7179cc
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Citations in the corpus
- Apoptotic pathways: paper wraps stone blunts scissors. (2000, neutral): “(Meisenholder et al., 1996; Matsuyama et al., 2000), sug- Mol.”
- Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. (2011, methodology): “These tools can be used together with assessments of cytosolic pH using similar cytosol-targeted pH-sensitive fluorescent fusion reporter proteins (42) or the pH-sensitive fluorophore 2′-7′-bis(carboxyethyl)-5(6)carboxyfluorescein acetoxymethyl ester (BCECF-AM) (43), to directly calculate ΔpHm acros”
- Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. (2001, background): “Mitochondrial hexokinases are activated by glucose and inhibited by glucose-6-phosphate that dissociates the enzyme from the mitochondrial membrane likely through a change in conformation (Wilson 1995; Mulichak et al. 1998).”
- The lysosome: from waste bag to potential therapeutic target. (2013, background): “Another explanation for the preserved proteolytic action of cathepsins is cytosolic acidification, which have been described in a number of experimental systems (Gottlieb et al., 1995; Matsuyama et al., 2000; Nilsson et al., 2006; Appelqvist et al., 2012a).”
- Energy Substrate Modulates Mitochondrial Structure and Oxidative Capacity in Cancer Cells (2004, neutral): “4 after the addition of an oxidizable substrate (pyruvate/lactate), whereas a study performed in 293T and Jurkat cell lines (28) gave pHm value of 8.”