Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses.
By Pramod Kumar Srivastava. Annual Review of Immunology, 2002
924 citations recorded by the source corpus.
Subfields: Cell Biology, Infectious Diseases, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/8e91d7a3a5b31cefed00c2d491521ed4dff16f9a
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Citations in the corpus
- Translating innate immunity into immunological memory: implications for vaccine development. (2006, positive): “Such ‘‘danger signals’’ (Matzinger, 1994) include heat-shock proteins (Srivastava, 2002) and uric-acid crystals (Shi et al.”
- Exosomes: composition, biogenesis and function (2002, background): “These ubiquitous proteins are involved in antigen presentation, as they can bind antigenic peptides and participate in loading peptides onto MHC molecule”
- Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications (2005, background): “The elevated Hsps may also provide a tempting target for immunotherapy protocols because they are able to chaperone tumor antigens and act as biological adjuvants to break tolerance to tumor antigens and cause immune killing by cytotoxic CTL and tumor regression (Arnold-Schild et al 1999; Belli et a”
- Indirect activation of naïve CD4+ T cells by dendritic cell–derived exosomes (2002, background): “The heat shock protein hsc73, involved in peptide delivery to antigen-presenting cells (APCs”
- Immunotherapy and chemotherapy — a practical partnership (2005, background): “This balance between pro- and anti-inflammatory mediators might block CTL induction, but additional chemotherapy could increase the pro-inflammatory mediators such as HSPs to sufficient levels to induce CD8 + T-cell response”
- Cancer vaccines: between the idea and the reality (2003, background): “They efficiently deliver antigen to the MHC class I pathway and in the process activate APC”