Immunotherapy and chemotherapy — a practical partnership

By R. Lake, B. Robinson. Nature Reviews. Cancer, 2005

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Regulation of PD-L1: a novel role of pro-survival signalling in cancer. (2016, background): “While immunocompromised individuals are associated with increased cancer incidence and poorer prognosis, it is now known that effective immune responses are involved in destruction of cancer cells by many therapeutic agents [1-3].”
Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer (2013, background): “Other drugs trigger apoptosis by inducing release of cytochrome c from mitochondria.(94) The degree of TCD correlates with clinical outcome in several tumor settings.”
Extending the Boundaries of Cancer Therapeutic Complexity with Literature Data Mining (2022, background): “This is reasonable, since some chemotherapies cause immunogenic cell death, which can educate the immune system to attack the dead cancer cells, resulting in a more efficient attack on living cancer cells following the immunotherapy 20 .”