Exosomes: composition, biogenesis and function
By C. Théry, L. Zitvogel, S. Amigorena. Nature reviews. Immunology, 2002
5,131 citations recorded by the source corpus.
Subfields: Microbiology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/f5689bd2fd80b79e1c165bee5a87c4423c44222a
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In Microbiology
In Molecular Biology
- C. Théry
- G. Raposo
- Suresh Mathivanan
- Richard J. Simpson
- Hina Kalra
- Raghu Kalluri
- S. Kourembanas
- G. Drummen
Citations in the corpus
- Body fluid derived exosomes as a novel template for clinical diagnostics (2011, background): “Exosomes are released from cells by fusion of MVBs with the plasma membrane and carry membrane antigens to the outside [1,2].”
- Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake (2016, neutral): “…that these EVs contain various proteins, sugars, lipids, and a wide variety of genetic materials, such as DNA, mRNA, and non-coding (nc)RNAs with the content protected from proteases and nucleases in the extracellular space by the limiting membrane (Henderson and Azorsa 2012; Théry et al. 2002).”
- Exosomal cell-to-cell transmission of alpha synuclein oligomers (2012, background): “Exosomes can interact with recipient cells in different ways, including endocytosis, fusion with the plasma membrane, receptorligand-binding or attachment [78,95-97].”
- Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes (2012, background): “Furthermore, in agreement with prior exosome proteomics studies, components of the ESCRT complex and exosomal marker proteins as Flotillin-1 and -2, CD9, CD63, heat shock protein 70 (HSP70), MHC molecules, CD81, CD82 and proteins from the Rab family could be identified in our samples (3,7,39,40).”
- The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes (2012, methodology): “The blotting membrane was blocked with bovine serum albumin and incubated with CD63 antibody (Abcam, Cambridge, UK) and with TSG101 (Abcam, Cambridge UK) followed by incubation with horseradish peroxidase-coupled secondary antibody (Cell Signaling Technology, Inc. Danvers, MA).”
- Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies (2013, neutral): “Such translocation may also occur during exosome formation [116].”
- A Review of Exosomal Isolation Methods: Is Size Exclusion Chromatography the Best Option? (2020, background): “The presence of exosomes was relatively ignored (classified as ‘cellular dust’) until interest was revived with discoveries demonstrating their capacity to serve as mediators of intercellular communication [9], potential drug delivery vectors [10], and bio-markers of various chronic and acute diseas”