Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

By N. Sanai, A. D. Tramontin, A. Quiñones‐Hinojosa, N. Barbaro, N. Gupta, S. Kunwar, M. Lawton, M. McDermott, A. Parsa, J. M. Verdugo and 2 more. 2004

1,380 citations recorded by the source corpus.

Subfields: Cancer Research, Developmental Neuroscience, Neurology

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “Because of limitations of tools that can be applied to humans, there is still ongoing debate about the existence of adult SVZ neurogenesis and a prominent RMS of new neurons in humans (Curtis et al., 2007; Sanai et al., 2004; Wang et al., 2011).”
Making a tumour's bed: glioblastoma stem cells and the vascular niche (2007, background): “Studies conducted over the past 10 years have identified stem cells with regenerative capacity in the adult mammalian brai”
Brain tumour stem cells (2006, background): “Interestingly, the subventricular zone seems to be present in the human adult brai”
Neuronal fate determinants of adult olfactory bulb neurogenesis (2005, background): “, even though RMS has not been observed in human brain”
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury (2006, methodology): “We prepared primary astrocytes from 2-d-old wild-type and conditional knockout mice as previously describe”
Dopamine depletion impairs precursor cell proliferation in Parkinson disease (2004, background): “There is now robust evidence for the presence of neural stem cells in the adult human subependymal zone, although there was no evidence of a massive chain migration of subependymal zone–derived precursors to the olfactory bul”
Functional organization of the transcriptome in human brain (2008, background): “Although the cellular composition and cytoarchitecture of the adult human SVZ have been extensively characterize”
The biology of cancer stem cells. (2007, background): “In patients with AML, expression of Bmi-1 is higher in AML cells than in normal bone marrow (Park et al. 2003, Sawa et al. 2005).”
Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma (2004, background): “7 and 8) that comprise glia-like neural stem cells and their progeny (9, 10).”
Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration. (2014, methodology): “Based on the knowledge that polySia is a marker of adult neurogenesis in the rodent SVZ, immunostaining for polySia has been used to identify the presence of the SVZ/RMS system in rabbits (274, 373), non-human primates (165, 246, 365, 410), and humans (36, 101, 379, 404, 405, 540).”