Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

By S. Trifari, C. Kaplan, E. Tran, N. Crellin, H. Spits. Nature Immunology, 2009

1,052 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/8d09b444e39b78b1bbce8b6f39c40ea221cdc995

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Citations in the corpus

International Union of Basic and Clinical Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors (2014, neutral): “Thus, gut-homing molecules (CCR9, a4b7 integrin) are induced in gut-associated lymph nodes, whereas skin-homing molecules (CCR4, CCR10) are universally induced in all lymph nodes (Alvarez et al., 2007).”
From Vaccines to Memory and Back (2010, neutral): “Other effector (and memory) T helper cell subsets have been recently characterized in mice and humans, such as Th9 (Veldhoen et al., 2008) and Th22 (Duhen et al., 2009; Trifari et al., 2009) which may be involved in allergy and skin defense respectively.”
Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis (2009, neutral): “…questions, identification and quantification of human Th17, Th22, and Th1 cells by flow cytometric analyses has been described over the last several years (Acosta-Rodriguez et al., 2007; Annunziato et al., 2007; Wilson et al., 2007; Cosmi et al., 2008; Duhen et al., 2009; Trifari et al., 2009).”
Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab (2011, background): “Our understanding of human T H cell lineages continues to evolve as additional T H profiles, such as T H 22 and T H 9, are describe”
Regulation of the immune response by the aryl hydrocarbon receptor (2018, background): “AhR regulates IL-22 production in these cells, as well as the expression of additional factors important for their function in mucosal immunity (Basu et al., 2012; Duhen et al., 2009; Ramirez et al., 2010; Trifari et al., 2009; Yeste et al., 2014).”