Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide.

By Shijun Mi, Tao Cai, Yugang Hu, Yemiao Chen, E. Hodges, Fangrui Ni, Liang Wu, Shan Li, Huanyu Zhou, Chengzu Long and 3 more. Cell, 2008

1,319 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/885f68eedc40ec90991fcbd984ae37d4722fd9a1

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Citations in the corpus

PIWI-interacting small RNAs: the vanguard of genome defence (2011, result): “This would be in accordance with findings from the plant Arabidopsis thaliana , in which each AGO protein shows a unique 5′ nucleotide bias in the small RNAs with which it associate”
Human tRNA-derived small RNAs in the global regulation of RNA silencing. (2010, background): “RNaseP is the enzyme that cleaves off the 59 leaders of precursor tRNAs and may be required for the functioning of RNaseZ for at least some tRNAs (Nashimoto et al. 1999; Dubrovsky et al. 2004).”
The Structure of Human Argonaute-2 in Complex with miR-20a (2012, neutral): “Their 50 ends occupy a pocket within the Argonaute Mid domain, which may confer 50 end nucleotide preferences upon some Ago family members (Boland et al., 2010; Frank et al., 2010; Ma et al., 2005; Mi et al., 2008; Parker et al., 2005).”
Small RNA sorting: matchmaking for Argonautes (2010, background): “Recently, our understanding of small RNA-sorting determinants has expanded substantially, and Argonaute and RNA structural studies have begun to provide a mechanistic basis for observations from in vitro and in vivo analyse”
Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs[OPEN] (2013, background): “AGO1 and AGO10, the two AGO proteins examined to date with respect to the translational inhibition activity of plant miRNAs, have been shown to be required for this activity of miRNAs (Brodersen et al., 2008; Beauclair et al., 2010).”
miRBase: integrating microRNA annotation and deep-sequencing data (2010, methodology): “In addition, the Arabidopsis reads shown are isolated from different Argonaute complexes—the majority of reads are not associated with the microRNA AGO1 complex, rather with AGO4 (16).”
Small RNAs and Their Roles in Plant Development (2009, methodology): “The small RNAs that are associated with 5 of the 10 AGOs have been immunopurified and subjected to high-throughput sequencing (Mi et al. 2008, Montgomery et al. 2008a, Qi et al. 2006, Takeda et al. 2008).”
Plant microRNAs: new players in functional genomics (2013, neutral): “Among the 10 AGO family members, AGO1 was found to be one of the most important members for miRNA biogenesis and processing in plants (Vaucheret et al. 2004; Kinder and Martienssen 2005; Ronemus et al. 2006; Mi et al. 2008; Takeda et al. 2008).”
Roles of plant small RNAs in biotic stress responses. (2009, background): “Assuming the 5′ nt bias for sRNA sorting into specific AGOs applies to vsRNAs (44, 48, 68), viral production of large amounts of vsRNA with 5′-terminal U could possibly saturate AGO1 to impair its action in antiviral defense and possibly in innate immunity mediated by endogenous sRNAs.”
A three-dimensional view of the molecular machinery of RNA interference (2009, background): “In the plant Arabidopsis thaliana , distinct types of small non-coding RNA associate with different Argonaute proteins on the basis of the identity of the 5′ nucleotid”