Immune functions encoded by the natural killer gene complex

By W. Yokoyama, B. Plougastel. Nature reviews. Immunology, 2003

623 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/881292a02b8794419655d12d56eea134b279e1a0

How researchers see this paper

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In Immunology

1. A. Steinle
2. I. Waldhauer
3. É. Vivier
4. R. Vance
5. D. Raulet
6. S. Ugolini
7. W. Yokoyama
8. Gordon D. Brown

Citations in the corpus

• NK cells and cancer immunosurveillance (2008, background): “…transcripts (ILT) or the natural cytotoxicity receptor (NCR) NKp46, are encoded in the leukocyte receptor complex (LRC), whereas C-type lectin-like receptors (CTLR) of NK cells are encoded in the natural killer gene complex (NKC) (Lanier, 1998; Yokoyama and Plougastel, 2003; Kelley et al., 2005).”
• Dectin-1: a signalling non-TLR pattern-recognition receptor (2006, background): “Given the similarity of dectin-1 to other NK-cell-receptor-like C-type lectins, the endogenous ligand might be an MHC class I molecule or related protei”
• Functions of natural killer cells (2008, background): “In particular, NK cells express MHC class I–specific receptors and 'lose' inhibitory signals when encountering MHC class I–deficient hematopoietic cells in several in vitro and in vivo model”
• Cytokine-induced memory-like natural killer cells (2009, background): “Unlike adaptive T and B lymphocytes, NK cells do not somatically rearrange their receptor genes, but rely upon a finite number of germ line-encoded inhibitory and activating NK receptors capable of recognizing MHC class I and class I-like molecules (8, 9).”
• Self-tolerance of natural killer cells (2006, background): “MHC class I genes are inherited independently of NK-cell receptor gene”
• Origin and evolution of the adaptive immune system: genetic events and selective pressures (2010, background): “For example, in primates the NK receptors that interact with classical MHC class I molecules are members of the killer cell Ig-like receptor (KIR) family, but in rodents the corresponding receptors are C-type lectin-like molecules known as Ly49 receptor”