Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

By Djahida Bouskra, C. Brézillon, M. Bérard, C. Werts, R. Varona, I. Boneca, G. Eberl. Nature, 2008

1,084 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/855cde8e975a5b6d2c3e3c689c70c79ce53fd4e3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

Citations in the corpus

Innate Lymphoid Cells: a new paradigm in immunology (2015, background): “Although the development of lymph nodes and Peyer’s patches, induced by LTi cells, is programmed in the fetus, the formation of isolated lymphoid follicles (ILFs) in the intestinal lamina propria after birth is not (69).”
The Intestinal Microbiome in Early Life: Health and Disease (2014, background): “Experiments in germ-free animal models have shown that microbial colonization induces anatomical development of the intestinal epithelium into the typical microvilli pattern, increases epithelial cell turnover rates, and kick-starts the maturation of the gut-associated lymphoid (immune) tissue (GALT”
Gut microbiota in health and disease. (2010, background): “mature isolated lymphoid follicles (27).”
The Microbiome in Infectious Disease and Inflammation (2012, positive): “Constitutive NOD1 signaling by PGN from commensal gram-negative bacteria, such as the genus Bacteroides, is required for the induction and maintenance of ILFs (4).”
Microbiota in health and diseases (2022, background): “For example, current advances have shown that human microbiota is closely involved in nutrient extraction, metabolism, and immunity.(15) Microbiota may affect biological processes via several mechanisms.”
Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22 (2011, background): “Initial reports have demonstrated that in the absence of commensal bacteria, LTi-like ILCs are present in cyptopatches at normal frequencie”
Probiotics, gut microbiota, and their influence on host health and disease (2017, background): “They interact with specific pattern-recognition receptors present on the surface or in the organelle membrane of epithelial and dendritic cells, this interaction being responsible for not only some of the beneficial effects attributed to probiotics, but also key for the normal interaction of the int”
Interaction between microbiota and immunity in health and disease (2020, background): “Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) serves as an innate sensor assisting generation of adaptive lymphoid tissues and maintenance of intestinal homeostasis.(63) The bacterial sensor NOD2 prevents inflammation of the small intestine by restricting the growth of the co”
Role of the Microbiota in Immunity and inflammation (2014, background): “In the intestine, tertiary lymphoid structures such as isolated lymphoid follicle or crytopatches are induced after birth as a result of commensal exposure (Bouskra et al., 2008; Ohnmacht et al., 2011).”