Methylation as a Crucial Step in Plant microRNA Biogenesis

By Bin Yu, Zhiyong Yang, Junjie Li, S. Minakhina, Maocheng Yang, R. W. Padgett, R. Steward, Xuemei Chen. Science, 2005

1,147 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/7ec773f163a9237a06b94c624fef896df9a5c01a

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Citations in the corpus

Roles of plant small RNAs in biotic stress responses. (2009, background): “AGO1, ARGONAUTE1; ARF, auxin response factor; BAK1, BRI1-associated receptor-kinase 1; DCL1, Dicer-like1; DDL, DAWDLE; HEN1, HUA ENHANCER 1; HYL1, HYPONASTIC 1; Pst, P. syringae pv. tomato; R, resistance; RLK, receptor-like kinase; SCF, Skp, Cullin, F-box containing; SE, SERRATE.”
Gene silencing in plants using artificial microRNAs and other small RNAs. (2008, background): “Plant sRNA duplexes, including miRNA–miRNA* duplexes, are modified at the 3¢ terminal ribose position by the methyltransferase HUA ENHANCER 1 (HEN1) (Yu et al., 2005), which prevents uridylation and thus stabilizes the sRNAs (Li et al., 2005). ª 2008 The Authors Journal compilation ª 2008 Blackwell…”
microPrimer: the biogenesis and function of microRNA (2005, background): “The terminal methyl group is added by the S-adenosyl methionine (SAM)-dependent methyltranferase HEN1, and the modification of the miRNA by HEN1 either protects the miRNA from further modification or degradation, or may facilitate its assembly into the RISC (Boutet et al., 2003; Yu et al., 2005).”
Functions of microRNAs and related small RNAs in plants (2006, background): “The 3′ ends of miRNA duplexes are methylated by HEN”
Plant microRNAs: new players in functional genomics (2013, positive): “…were detected that involved miRNAs, such as root initiation and development (Montgomery et al. 2008; Marin et al. 2010), vascular development (Yu et al. 2005; Donner et al. 2009), leaf morphogenesis and polarity (Palatnik et al. 2003; Mallory et al. 2004), floral differentiation (Chuck et…”
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. (2007, background): “sults in an RNA species that has an apparent mobility of two fewer nucleotides compared to the original RNA ( Yu etal.,2005 ).ThreedifferentpiRNAs areresistant tothisreaction (Figures 6A and S6), while within the same samples the miRNA let-7a is completely converted, indicating that either the 20 or”
Human tRNA-derived small RNAs in the global regulation of RNA silencing. (2010, background): “RNAi-related small RNAs have emerged early during evolution , and have subsequently been adapted as guide RNAs in a wide range of genome and gene regulatory pathways (for review, see Zamore and Haley 2005; Ghildiyal and Zamore 2009).”
MODOMICS: a database of RNA modification pathways. 2008 update (2008, background): “Modifications have been found to occur in microRNA (1).”
Post-transcriptional small RNA pathways in plants: mechanisms and regulations. (2006, background): “2002) RNA methylase (Li et al. 2005; Yu et al. 2005) PTGS-deficient (Boutet et al.”
Small RNA sorting: matchmaking for Argonautes (2010, methodology): “Processed miRNA duplexes are modified by the methyltransferase HUA ENHANCER 1 (HEN1”