Post-transcriptional small RNA pathways in plants: mechanisms and regulations.

By H. Vaucheret. Genes & Development, 2006

811 citations recorded by the source corpus.

Small RNAs are riboregulators that have critical roles in most eukaryotes. They repress gene expression by acting either on DNA to guide sequence elimination and chromatin remodeling, or on RNA to guide cleavage and translation repression. This review focuses on the various types of post-transcriptional small RNA-directed pathways in plants, describing their roles and their regulations.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/15ec7acbb0d9f65f50fce43620ea38578ba28b8f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Plant Science

Citations in the corpus

Improvement of salinity stress tolerance in rice: Challenges and opportunities (2016, background): “Unlike TGS however, PTGS is often reversible and used as a quick acting regulator of transcript half-life and subsequent gene expression [152].”
XRN 5’→3’ exoribonucleases: Structure, mechanisms and functions (2013, background): “One example of this in both plants and animals occurs via small RNAs (20–30 nt long) acting as guides in silencing complexes by directingAGOproteins to specific target mRNAs [34–37].”
Non‐coding RNAs: regulators of disease (2010, background): “Indeed it appears that RNA signalling is central to all complex genetic phenomena in the eukaryotes, including transcriptional and post-transcriptional gene silencing [13–22], hybrid dysgenesis [15,23], Xchromosome dosage compensation and allelic exclusion [24,25], germ cell reprogramming [26] and p”
Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. (2006, background): “For example, PTGS of a sense transgene (S-PTGS) is triggered by dsRNAs that are converted from single-stranded RNAs (ssRNAs) by RDR6 with the help of SGS3 (Vaucheret 2006).”
Transgenerational response to stress in Arabidopsis thaliana (2010, background): “Although our work has some indications that such mechanism of stress memory inheritance exists, it remains to be established whether there is a difference in smRNAs pools from gametes of stressed and nonstressed plants; and whether there is a link large number of developmental, physiological and str”
Uncovering Small RNA-Mediated Responses to Phosphate Deficiency in Arabidopsis by Deep Sequencing1[W][OA] (2009, background): “…antisense transcript-derived siRNAs, and heterochromatin siRNAs according to their genomic origin and the interaction of distinct components (Vaucheret, 2006; Vazquez, 2006). ta-siRNAs are phased 21-nucleotide RNA molecules whose synthesis is triggered by the cleavage of miRNA on the TAS…”
Revisiting the principles of microRNA target recognition and mode of action (2009, background): “In both kingdoms, miRNAs have vital roles in development, stress adaptation and hormone signallin”
Micro RNAs and Short‐interfering RNAs in Plants (2007, background): “An initial DCL1-dependent, miRNAguided cleavage of tasiRNA primary transcript defines the 5’ and 3' ends of the transcript which can be converted into dsRNA by RDR6 and SGS3 and sets the 21-nt phase for accurate tasiRNA formation by DCL4 in Arabidopsis (Allen et al. 2005; Gasciolli et al. 2005; Yosh”
Gene silencing in plants using artificial microRNAs and other small RNAs. (2008, background): “Transgene-mediated gene silencing can overcome some of these shortcomings through tissue-specific, inducible and partial gene inactivation, or simultaneous targeting of several, sequence-related genes.”
Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide. (2008, background): “Arabidopsis contains a complex system of small RNAs including miRNAs and several classes of endogenous siRNAs (Vaucheret, 2006). miRNAs are derived from primary transcripts that adopt characteristic stem-loop structures.”
The Genetic Signatures of Noncoding RNAs (2009, background): “Despite the now known importance of miRNAs in the control of gene expression [67,132], only four miRNA loci have been identified in intense genetic screens in C.”
MicroRNAs as master regulators of the plant NB-LRR defense gene family via the production of phased, trans-acting siRNAs. (2011, background): “Another major class of small RNAs are heterochromatic siRNAs (hc-siRNAs) that suppress the activities of transposable elements and maintain genome stability via DNA methylation and chromatin modifications (Vaucheret 2006).”
Synthetic Hexaploid Wheat: Yesterday, Today, and Tomorrow (2018, background): “Small RNAs are 21–24 nucleotide non-coding RNAs that regulate gene expression by post-transcriptional mechanisms and through epigenetic modifications [84,85].”
Antiviral immunity directed by small RNAs. (2007, positive): “In Arabidopsis, DRB1 (also known as HYL1) facilitates DCL1-dependent miRNA production from their fold-back precursors (Bartel, 2004; Vaucheret, 2006), and DRB4 enhances DCL4 processing of long dsRNAs involved in endogenous gene silencing (Vaucheret , 2006; Figure 1).”