NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis

By U. Ozerdem, K. Grako, Kimberlee Dahlin‐Huppe, E. Monosov, W. Stallcup. Developmental Dynamics, 2001

615 citations recorded by the source corpus.

Subfields: Immunology and Allergy, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7a5367acf69d95ba69e3ce5814d178982d207d7b

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Citations in the corpus

Endothelial-pericyte interactions in angiogenesis (2003, background): “1992), high molecular weight melanoma antigen (HMW-MMA) (called NG2 in the mouse) (Ozerdem et al. 2001; Ruiter et al. 1993), platelet-derived growth factor b-receptor (PDGFR-b) (Lindahl et al.”
A perivascular origin for mesenchymal stem cells in multiple human organs. (2008, positive): “Confirming and extending previous observations (Ozerdem et al., 2002; Middleton et al., 2005; Sacchetti et al., 2007), we have validated the CD146+ NG2+ PDGFRb+ ALP+ CD34 CD45 vWF CD144 phenotype as an indicator of pericyte/perivascular cell identity throughout human fetal and adult organs.”
Revisiting Cardiac Cellular Composition (2015, methodology): “An anti-NG2 antibody was used to identify pericytes.(26) We found that VSMCs and pericytes could be observed after isolation with protocol 2 (Online Figure V), suggesting that this population of cells will be included when determining relative cardiac cell proportions.”
Specialization of tumour vasculature (2002, neutral): “cgi?l=13003">NG2 proteoglycan , also known as melanoma-associated chondroitin sulphate proteoglycan, is a membrane-spanning cell-surface protein that is expressed in the neovasculature of tumours, regenerating tissues and in fetal vessel”
Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors (2008, methodology): “To determine the identity of the cells expressing VEGF in the GCL, flatmounted retinas from adult VEGF-LacZ mice [28] were colabeled for lac-Z and for NG2, the chondroitin sulfate proteoglycan, as a pericyte marker [29].”
NG2 cells generate both oligodendrocytes and gray matter astrocytes (2007, methodology): “DsRed is present in mural cells of the cerebral vasculature In addition to glial cells, DsRed was expressed on vascular cells, as previously reported for NG2 (Ozerdem et al., 2001).”
Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery (2009, methodology): “We used antibodies against α-SMA (mouse, monoclonal, Neomarkers, MS-113-P1) or NG2 chondroitin sulfate proteoglycan (rabbit, polyclonal, Chemicon, MAB5384 (ref”
The role of pericytes in blood-vessel formation and maintenance. (2005, background): “Studies of the corpus luteum have suggested that pericytes are also capable of guiding sprouting processes by migrating ahead of endothelial cells and expressing VEGF (Ozerdem and Stallcup, 2003; Ozerdem et al., 2001; Reynolds Bergers and Song: Pericytes in blood vessel formation and maintenance”
Imaging of angiogenesis: from microscope to clinic (2003, neutral): “, high-molecular-weight melanoma-associated antigen (NG2”
Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts. (2008, result): “Furthermore, the large overall similarity between pericytes and MSC is in line with published data showing similar immunophenotype [25,52,53] and differentiation potential in vitro [19,21,22,54,55] and in vivo [56].”