Limbic-frontal circuitry in major depression: a path modeling metanalysis

By David A. Seminowicz, Helen S. Mayberg, Anthony Randal McIntosh, K. Goldapple, Sidney H. Kennedy, Z. Segal, S. Rafi-Tari. NeuroImage, 2004

737 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/78375757672318474cc5a47dc98e585423723d41

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Citations in the corpus

A pathophysiological framework of hippocampal dysfunction in ageing and disease (2011, background): “A brain network linked to depression has been suggested based on the connectivity among some of these area”
Identifying major depression using whole-brain functional connectivity: a multivariate pattern analysis. (2012, background): “All of the above altered connections fall into the limbic-cortical dysregulation model (Mayberg, 2003; Seminowicz et al., 2004; Drevets et al., 2008; Price and Drevets, 2010) and may negatively affect the regulation of mood and affect (Savitz and Drevets, 2009).”
Deep brain stimulation for treatment-resistant depression. (2005, positive): “Our own studies have demonstrated consistent involvement of the subgenual cingulate (Cg25) in both acute sadness and antidepressant treatment effects, suggesting a critical role for this region in modulating negative mood states (Mayberg et al., 1999; Seminowicz et al., 2004).”
The link between childhood trauma and depression: insights from HPA axis studies in humans. (2008, background): “Multivariate analyses revealed that these responder groups already had different neural activation patterns before treatment (Seminowicz et al., 2004).”
Deep Brain Stimulation to Reward Circuitry Alleviates Anhedonia in Refractory Major Depression (2008, background): “…in acute induced sadness, is metabolically overactive in treatment-resistant depression, and that clinical improvement after pharmacotherapy and psychotherapy is correlated with decreases in its metabolic activity (Auer et al, 2000; Mayberg et al, 1999; Mirza et al, 2004; Seminowicz et al, 2004).”
Cognitive therapy vs. medications for depression: Treatment outcomes and neural mechanisms (2008, background): “For example, Mayberg and colleagues have cited evidence in support of their hypothesis that an extensive brain network is impaired in individuals with the full syndrome of depressio”
Posttraumatic stress disorder: a state-of-the-science review. (2006, methodology): “In an attempt to define common denominators of successful treatments, Seminowicz et al. (2004) developed a simplified 7-region model derived from the results of these treatment studies; this was mathematically tested using structural equation modeling.”
Brain volume abnormalities in major depressive disorder: A meta‐analysis of magnetic resonance imaging studies (2009, background): “Several lines of evidence suggest the presence of specific neural circuits within the limbic-cortical system that mediate stress-responsiveness, mood and emotional regulation [Brody et al., 2001; Seminowicz et al., 2004; Tekin and Cummings, 2002].”
Adult hippocampal neurogenesis in depression (2007, background): “The success of this endeavor relied on the identification of subgenual cingulate (Cg25) as a key neural substrate of the pathophysiology of depressio”
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “Unauthorized reproduction of this article is prohibited. hippocampus and other limbic nuclei (Goldapple et al., 2004; Seminowicz et al., 2004).”
Inflammation Causes Mood Changes Through Alterations in Subgenual Cingulate Activity and Mesolimbic Connectivity (2009, positive): “The sACC has become increasingly recognized as a key node in functional and anatomical models of mood regulation (36) and coordination of emotional processing.”