Alginate Overproduction Affects Pseudomonas aeruginosa Biofilm Structure and Function
By M. Hentzer, Gail M. Teitzel, G. J. Balzer, A. Heydorn, Søren Molin, M. Givskov, M. Parsek. Journal of Bacteriology, 2001
687 citations recorded by the source corpus.
Subfields: Architecture, Education, Media Technology
View Paper: https://www.semanticscholar.org/paper/7200d43badcae34bbc8ec93b6a33934caa9981d9
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Architecture
In Education
In Media Technology
Citations in the corpus
- Heavy Metal Resistance of Biofilm and Planktonic Pseudomonas aeruginosa (2003, methodology): “resistance of free-swimming organisms (7, 13).”
- Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms (2003, background): “aeruginosa PAO1 and PA14 defective in alginate production produce SSA biofilms just like the wild-type strains (Hentzer et al., 2001; Wozniak et al., 2003).”
- Screening for Quorum-Sensing Inhibitors (QSI) by Use of a Novel Genetic System, the QSI Selector (2005, methodology): “Bacterial viability in biofilm cultures was assessed using the LIVE/ DEAD BacLight bacterial viability staining kit (Molecular Probes, Inc., Eugene, Oreg.) as described previously ( 24 ).”
- Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation (2002, methodology): “Additionally, measurements of viable biomass of GFP-tagged PA14 and RSCV cells using CSLM analysis”
- Biosynthesis of Extracellular Polymeric Substances (EPS) and Its Role in Microbial Biofilm Formation (2007, background): “[67] the extracellular alginate overproduction also increased the tobramycin resistance of Pseudomonas spp.”
- Pathophysiology and management of pulmonary infections in cystic fibrosis. (2003, background): “Subsequently, the presence of local hypoxia within mucus plaques in the airways has been suggested to increase Pseudomonas alginate production (97), which may lead to increased biofilm formation (Figure 6) (138).”
- Biofilms as complex differentiated communities. (2002, background): “Hentzer et al. attribute this difference to differing nutrient conditions.”
- A component of innate immunity prevents bacterial biofilm development (2002, methodology): “Pseudomonas aeruginosa biofilms for susceptibility tests were grown in a rotating disc reacto”
- Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms (2009, background): “In comparison with biofilms made by the nonmucoid strain PAO1, an isogenic strain that has been made mucoid as a result of deregulation of the alginate synthesis genes makes a biofilm that is 1,000 times more resistant to the antibiotic tobramycin (129).”