Genetic engineering approaches to improve the bioavailability and the level of iron in rice grains

By P. Lucca, R. Hurrell, I. Potrykus. Theoretical and Applied Genetics, 2001

396 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/623852fe75b1908629ce66cd3b8d981767c37f92

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Citations in the corpus

Phytase for food application (2006, background): “So far, only one transgenic plant heterologously expressing a phytase has been developed in order to deal with the issue of dietary phytate in human nutrition (42,146).”
Phytochelatins and metallothioneins: roles in heavy metal detoxification and homeostasis. (2002, background): “As more attention is paid to the nutritional composition of foods as opposed to simple calorific value, MTs may provide one mechanism to manipulate metal concentration in seeds (44).”
Iron transport, deposition and bioavailability in the wheat and barley grain (2009, background): “fumigatus phytase were boiled for 20 min, only ~8% of the initial phytase activities were retained, indicating that the in planta produced enzyme was unable to refold and regain activity (Brinch-Pedersen et al. 2006; Lucca et al. 2001).”
Biofortification of crops with seven mineral elements often lacking in human diets--iron, zinc, copper, calcium, magnesium, selenium and iodine. (2009, background): “Attempts to increase protein cysteine concentrations in edible tissues have also proved successful on occasion (Chakraborty et al., 2000; Lucca et al., 2001, 2002; Sun & Liu, 2004; Welch & Graham, 2004), but not always (Tabe & Droux, 2002; Hagan et al., 2003; Zhang et al., 2003a; Chiaiese et al.,…”
Enrichment of cereal grains with zinc: Agronomic or genetic biofortification? (2007, background): “Transforming rice with ferritin gene from soybean (Goto et al. 1999; Qu et al. 2005) or French bean (Lucca et al. 2001) increased grain Fe concentrations.”
Producing more with less: Strategies and novel technologies for plant-based food biofortification (2013, background): “Lucca et al. (2001) transformed rice with an endogenous cysteine-rich metallothionein-like gene (rgMT), alongside a phytase from Aspergillus niger and the ferritin gene from Phaseolus vulgaris, under an endosperm specific promoter, and obtained complete degradation of phytate in the seeds.”
Enhanced iron and zinc accumulation in transgenic rice with the ferritin gene (2003, background): “Although similar observations have been made previously [5,10,14,30], no data have been shown after milling of the rice grains.”
Chapter 4 Iron Dynamics in the Rhizosphere: Consequences for Plant Health and Nutrition (2008, neutral): “, 1999), rice (O. sativa, Goto et al., 1999; Lucca et al., 2001; Vasconcelos et al., 2003), wheat (T.”
Molecular genetic approaches to increasing mineral availability and vitamin content of cereals (2007, background): “fumigatus (Lucca et al., 2001) and the yeast Schwanniomyces occidentalis (Hamada et al.”
Biofortification of crops for reducing malnutrition (2012, background): “Lucca et al. (2001) introduced a fungal gene encoding the enzyme phytase which breaks down phytate, thus improving the bioavailability of iron in rice diets.”